Memory B cell

Memory B cells are a B cell sub-type that are formed following primary infection. When a B cell is activated, by recognizing a specific antigen, it proliferates to form antibody producing plasma cells and long-lived memory cells. The memory B cells are specific for the antigen that first stimulated their production. If this antigen is encountered again, memory B cells can recognize it and quickly proliferate. This forms a new generation of antibody-producing plasma cells. This means that the antibody response is much more rapid in subsequent infections, than in primary infection, reducing the chance of symptom development. This is the principle behind vaccination.