Phagocyte
A
phagocyte is a
cell that ingests and destroys foreign matter such as
microorganisms or debris via a process known as
phagocytosis, in which these cells ingest and kill offending cells by a process analogous to cellular
digestion, usually using
lysosomes which carry potent enzymes that digests cell components such as other
lipids or
proteins. These phagocytes are extremely useful as an initial
immune system response to tissue damage.
The word 'phagocyte' literally means 'eating cell', originating from the Greek word 'phagein', meaning 'eat'.
They are also involved in cell death, usually
programmed cell death through
apoptosis, in which the phagocytes are responsible for cleaning up the debris and effectively "recycling" the dead cell parts. They are capable of cleaning up the debris of
necrosis, but this is less orderly than apoptosis. Because the resulting disorder makes it more difficult to pick up debris, and unlike apoptosis, cells which undergo necrosis does not transmit the proper signals that alert phagocytes to a dying cell, and therefore is less effective.