Expert: Glen Aukerman, M.D. - 10/17/2006

Question
Glen thanks for your response,but I was tested previously for celiac and tested negative  
Results :- Gliadin IgA(EIA) 4 units Normal<20
         Total IgA       1.41 g/l   (0.85-3.5)
         Serum Immunoglobin E  118 IU/ml 0-100*
     Note:Atopic genesis highly probable.

Could you interpret the bottom two lines?

I'm assuming negative gliadin means I'm not celiac? Does this mean I'm not allergic to gluten also? or is gluten intolerance a different  issue? my food IgG tested  strong positive to wheat and rye, is this gluten that is common to both these grains and causing the problem or was this ruled out with the gliadin test.   Thanks John
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Followup To

Question -
Dear Glen, I have just received back my results from an intestinal permeability test and are as follows:-
lactulose recovery    0.56*H %   <0.30  REF RANGE
mannitol recovery     19.3%     9.5-25.0    "
lactulose-mannitol ratio 0.029    <0.035    "
6 hour collection        0.400 litres

How would you interpret these results -  LGS ?


A recent IgG 93 FOOD SENSITIVITY PANEL showed 17  mild to very stong positive results to different foods some of which I  had been eating eg wheat,rye,almonds,walnuts to name a few.

A recent gastroscopy discovered gastritis and duodentis but all the mainstream gastro wants to do is prescibe  losec whereas I  think I probably have low acid(how could I test for low or high)) and that food sensitivities and allergies are probably causing inflamation not the high acid that he thinks.
What are your thoughts and how would you takle this?

Also recent ultrasound of neck has picked up 1.3 cm nodule which I am to have a nuclear medice thyroid test --is this the usual next step of evaluation?

Also recent runs of ectopics (PAC'S &PVC'S holter showed 1500 in 24 hour period)) have increased my anxiety levels yet echo and thallium cardio stress test come back fairly normal.I think a "chicken or egg" first problem-delayed food intolerance create gastric disturbance and/or pac's,pvc's create anxiety create further pac's,pvc's more anxiety adrenaline release all creating vicious circle?

I'm sick of being told it is all in the mind(been prescibed xanax for the anxiety) even though I have  many health issues which I believe probably have a root cause(I'm thinking mainly gut related).I take .5gm xanax 3 times a day but worried about dependence,but doc told me this is extremely low dose and will be easily weaned off.Any thoughts here?

Would dearly appreciate your thoughts( not medical advice) and what you might ,possibly do if you were in a similar situation

Yours thankfully JohnMartin Melbourne Australia

Answer -
lactulose recovery    0.56*H %   <0.30  REF RANGE
How would you interpret these results -  LGS ?
Ans: Celiac disease causing a secondary lactose intolerance, autoimmune disorder, and


A recent IgG 93 FOOD SENSITIVITY PANEL showed 17  mild to very stong positive results to different foods some of which I  had been eating eg wheat,rye,almonds,walnuts to name a few.
Ans: Celiac disease causing a secondary lactose intolerance, autoimmune disorder, and false positive food allergies.

A recent gastroscopy discovered gastritis and duodentis but all the mainstream gastro wants to do is prescibe  losec whereas I  think I probably have low acid(how could I test for low or high)) and that food sensitivities and allergies are probably causing inflamation not the high acid that he thinks. What are your thoughts and how would you takle this?
Ans: Celiac disease causing a secondary lactose intolerance, autoimmune disorder, and false positive food allergies, therefore you need to go on a gluten free diet, and avoid omega-6 plant oils

Also recent ultrasound of neck has picked up 1.3 cm nodule which I am to have a nuclear medice thyroid test --is this the usual next step of evaluation?
Ask for a TPO blood test for Hashimoto's thyroiditis which also comes from Celiac disease so also request a HLA DQ 2,8 genetic test for celiac disease

Also recent runs of ectopics (PAC'S &PVC'S holter showed 1500 in 24 hour period)) have increased my anxiety levels yet echo and thallium cardio stress test come back fairly normal.I think a "chicken or egg" first problem-delayed food intolerance create gastric disturbance and/or pac's,pvc's create anxiety create further pac's,pvc's more anxiety adrenaline release all creating vicious circle?
Ans: comes from too much omega-6 plant oils and too little magnesium oxide in your diet


I'm sick of being told it is all in the mind(been prescibed xanax for the anxiety) even though I have  many health issues which I believe probably have a root cause(I'm thinking mainly gut related).I take .5gm xanax 3 times a day but worried about dependence,but doc told me this is extremely low dose and will be easily weaned off.Any thoughts here?
Ans: even anxiety and depressive disorders come from too much omega-6 plant oil and too little omega-3 foods or fish oil, like local lamb not fed corn and seafoods not farm fed and avoid poultry fed corn which accumulates too much omega-6 plant oil in the fish or poultry


Answer
Serum Immunoglobin E  118 IU/ml 0-100*
    Note:Atopic genesis highly probable.
Could you interpret the bottom two lines?
Answer: This means you have atopic eczema as source of Ig E elevation.

I'm assuming negative gliadin means I'm not celiac?
Answer: Not really, this test has a 40% false negative, need to ask for a HLA DQ 2,8 which is 97% accurate.

Does this mean I'm not allergic to gluten also? No

or is gluten intolerance a different  issue? Different

my food IgG tested  strong positive to wheat and rye, is this gluten that is common to both these grains and causing the problem or was this ruled out with the gliadin test.
Answer: No,the test you had is only of value if positive