Ask the Veterinarian/Ciprofloxacin


Skin Culture Report
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Culture Report Page 2
Culture Report Page 2  
My dog has tested positive in a skin culture for pseudomonas and needs to take ciprofloxacin 250mg tablets twice a day. He has also tested positive for MRSP-4+ and could not tolerate chloramphenicol. I am having the vet give him almost daily chlorhexidine baths and using muricin topically. But my main question for you is can the 250mg cipro tablet be crushed and added to food? He has refused to take in pill form no matter how it is disguised. Can this pill be crushed into a powder safely? Thank you very much.

Ciprofloxacin tablets in the dog are not well absorbed if at all!!! Almost half of the dogs given tablets in experimental studies did not get much of a blood level to ciprofloxacin.  Cipro in a liquid form is somewhat better, absorption is almost 70%...still not very reliable.

Enrofloxacin (Baytril) or Marbofloxacin (Zenequin) would be much better to use if you are going to use a fluoroquinolone type of drug.  These drugs are well absorbed from the dog and are converted to ciprofloxacin within the dog's body.

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Dr. Louis N. Gotthelf


Dermatology and ear diseases of dogs and cats


I am the author of "Small Animal Ear Diseases; An Illustrated Guide" published by W.B. Saunders. I have over 25 years of clinical experience with a special interest in dermatologic conditions and ear diseases.

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