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Ask the Veterinarian/4 year old maine coon female problems with vaccinations


My four year old female Maine Coon  cat seems to be having a reaction to her vaccinations.  Brought her in on Friday day 1 for Rabies 1 year shot, DRTC + LEUK w/CALICIVAX, PROFENDER - large cat (she weights 12.4 lb) She does not have worms but this is what the Vet gives all cats.  She would not eat Friday evening or Saturday day 2.  Sunday day 3 she was eating and playing a little.  On Monday day 4 we woke up to 6 spots of vomit.  She continued to vomit 6 more times.  Back to Vet and she received a shot of CERENIA 8.9-11#, no fever.  Stopped vomiting but was lethargic and would not eat or drink.  on Wednesday day 5 (2 1/2 days not eating) went back to Vet and they did a Chemistry Panel - 6, gave her fluids Subcutaneous Therapy, force feeder her 60 cc.  Nothing seems to be physically wrong.  Brought her home still will not eating, drinking, is lethargic, but purrs when petted. On Thursday day 6 her stomach was very hard, tried to feed her then she threw up a lot.  We waited 3 hours then started force feeding her about 9 cc every 2 hours for a total of 45 cc and she kept it down.  Vet does not know what is wrong.  She says her only experience with vaccine side effects is fever & hives.  This was the most friendly cat, followed us all around the house & yard, loved to eat & play.  We are still force feeding her 72 cc a day and today is Sunday 9.  Do you have any ideas of what to do now?

Hi Patti,
To be honest this is pretty much outside of my realm of suggestions. Most vets would say give it some time but maybe you need to have her seen by a feline practitioner.

I am a vet tech, not a vet, and this is very unusual case which may or may not be related to the vaccinations.

I would HIGHLY suggest that you contact the manufactures of the vaccines she received- ALL of them. They WANT to know about ANY adverse reactions and will sometimes pay for treatments.

So please, contact them right away and I would highly recommend someone who specializes in feline medicine. They are more likely to have seen such a case.

I sincerely hope she gets well fast, but in the meantime, be proactive and call those companies.

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Jana Connell RVT, CVT


PLEASE READ BEFORE SUBMITTING TO ME: I am NOT a vet and do NOT diagnose diseases. That is only for a licensed Veterinarian to do. I will give you suggestions and steer you toward calling your vet for help. You can call the vet's office and talk to the technician there or the vet at times. Don't be afraid to call them! If you have a serious issue with your pet please post it to one of the veterinarians in here- I will tell you the same thing in my answer. IF your pet is injured or in an emergency situation, CALL YOUR VET- Do not wait and post in here. Just call the vet's office and get them in to see the vet right away. Critical treatment time is lost if you seek answers here when you should have your precious pet at the vets!! Don't sit at home waiting for an answer when your pet is critically ill or injured!! I can answer most questions about small animal and wildlife care as well as small animal nutrition. I can also answer questions about all phases of dental care for small animals. I DO NOT answer questions about birds (unless it is wildlife or songbirds) or HAMSTERS/GERBILS/CHINS/GUINEA PIGS/REPTILES/FROGS/RABBITS/PET BIRDS OF ANY KIND so please submit these questions to the appropriate sections. I, as well as other experts in here, do NOT do homework questions- that is for YOU to do! Please respect these rules for all of us. Thanks!


I have over 42 years experience in the field of veterinary medicine. I specialized in small animals and did wildlife rehab for over 25 years, mostly raptors, squirrels and opossums. I am a Small Animal Nutritional Consultant with 6 certificates from Hills Pet Foods, CNM and Purina. I also specialized in Small Animal Dentistry which is a field I truly love. I also Teach Veterinary Technology to working technicians who are studying to take their California Tests to become Licensed Technicians. They have to take both the VTNE (Veterinary Technician National Exam) and the California boards.

Audubon,World Wildlife Federation, American Society of Veterinary Dental Technicians.


Licensed with California and Oregon, RVT and CVT. Certified Veterinary Dental Technician Have over 1500 logged hours of Continuing Education Credits(that means I keep up to date!).

Awards and Honors
Nominated for Expert of the Month for the last 5 years.

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