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Asthma/Elevated IGG Levels
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Question
I haven't been feeling too well for the past year and have been diagnosed with autoimmune chronic hives. I'm under the care of a rhumatologist and an allergist. While I have several environmental allergies, they have associated my hives to autoimmune hives. All my autoimmune markers have come back normal except for my IGG levels which are as follows:
IgG, Serum High 1730 (reference range 694 to 1618)
IgG 2 Hight 816 (reference range 241 to 700)
My IgG 1, IgG 3, and IgG 4 levels came out normal.
My Rhumatologist is out of town for 10 days and I am concerned as to what the high IgG Serum and IgG 2 levels means. Any feed back would be appreciated.
Thanks for all your help!
Hi Shelly,
Of the five major immunoglobulins, IgG is the smallest antibody in size, but the most common of the group (75-80%), and is found in all body fluids.
IgG are very important in fighting bacterial and viral infections. Based upon that, you may have an infection in your system at this time. Have you been feeling under the weather, compared to your normal day to day activity?
Regarding the specific individual IgG-2 antibody, it correlates with some bacterial infections, such as pseudomonas, pneumococcal or H. influenza type B infections.
This is on the edge of my edge of my expertise, and for further discussion, I'd follow up with your allergist to allay your concerns.
Sincerely,
Marc
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Marc Rubin, RPh Asthma Educator
Expertise
I have worked directly with patients as well as caregivers for over 30 years. Have made presentations throughout Illinois educating school nurses as well as the teaching and coaching staff of public schools about asthma, and how they should respond to these students needs. Presented a public education program on asthma through the US Department of Public Health. Specialize in helping guide asthmatic patients to take control of their disease in order to live a near-normal, fully active life.
Experience
Practicing pharmacist for 34 years, specializing in asthma for past 7 years. Statewide education to nurses, teachers and athletic coaches regarding asthma. In addition, and closer to home. my wife and daughter both have asthma, and my son has exercise induced bronchospasm. I'm also on the advisory board of a medical education company, Emmi Solutions, and directly involved in the creation of public education programs for asthma, COPD and diabetes.
Organizations
American Academy of Allergy, Asthma and Immunology (AAAAI) / Sports Medicine Committee, American Thoracic Society (ATS). Chicago Asthma Consortium / Professional Development Committee, Respiratory Health Association of Metropolitan Chicago: Development Committee for AE-C prep class, and presenter.
Publications
AAAAI PowerPoint on the new guidelines for EIB (Exercise Induced Bronchospasm)
Education/Credentials
BScPharm, RPh, AE-C (NAECB Certified asthma educator), NIPCO Certified Respiratory Care Pharmacist
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