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Biology/Blood Brain Barrier

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Question
I have been searching the internet and my extensive library on nutrition and can not find a list of nutrients (vitamins, amino acids etc) that can cross the BBB.

I was wondering if you know of what nutrients or have a list of what nutrients cross the BBB?

Answer
Hi Karoly:  Thanks for your question.

I don't know of any list of substances that can pass the BBB.  The rules for entry are highly variable, depending on what the brain needs, what is available and what (if any) stress the organism is facing.  It's also important to remember that the BBB is not a static wall, but a live membrane with transporters that can facilitate entry of selected substances.  The ability of nutrients to pass the BBB will have any number of variables, and will vary by particular location in the brain.

Here's a link that I found:
http://books.google.com/books?id=rbuqS2Isow0C&pg=PA83&lpg=PA83&dq=blood+brain+ba...

You'll have to copy and paste it, it's a Google Books link.

Here's an article, but you'll have to pay for total access:
http://www.springerlink.com/content/r43063375j51w730/

Hope this helps, write back if you have more questions.

FM Rollwagen, PhD

Biology

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Florence M Rollwagen

Expertise

I can answer questions in biology, microbiology and immunology on the undergraduate or graduate level. I can also address medical and health concerns regarding alternative medicine, autoimmune diseases (lupus, MS) liver disease and intestinal problems.

Experience

I have over 20 years experience in research and teaching at the medical/graduate level, and 5 years teaching college biology and microbiology. My expertise is in microbiology and immunology, specifically the biology of cytokines and soluble immune response modifiers. I also carried out original research in blood substitutes and shock/trauma.

Organizations
American Association of Immunologists (AAI) American Association for the Advancement of Science (AAAS)

Publications
Journal of Experimental Medicine, Journal of Immunology, Cytokine, Shock, Experimental Hematology

Education/Credentials
BS biology 1966 MS biology 1968 PhD immunology 1979

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