Expert: Walter Hintz - 6/9/2009

Question
hi Walter
hope you can help
why do insulin levels drop as soon as the blood glucose levels stabilize?

Answer
 Hi Joanne
Hormones levels have set points that tend to fluctuate and these levels are controlled by feed back mechanisms. When the set point of insulin drops below the set point enzymes stimulate the beta cells in the pancreas to secrete more insulin. When there is an increase in blood glucose more insulin is used and goes below the set point causing an increase in production.  When glucose levels are back to normal so is insulin production.
 The usual feedback mechanism for hormones is called end product inhibition. Hormone secretions are the result of a chain of enzymes. When the level increases the hormone feeds back inhibiting the production.  When the required level is reached the inhibition is lifted.
I hope I have not confused you.  If so let me know