Expert: Walter Hintz - 3/7/2010

Question
A man with cystic fibrosis marries a homozygous dominant woman
1.  What is the genotype of the man?
2.  What is the genotype of the woman?
3.  What is the probability of producing a child with cystic fibrosis?
4.  What are hte genotypes of the offspring?
5.  What are the phenotypes of the offspring?

Answer
The genotype of the man has to be homozygouse for the disease. I cannot make any predictions unless I know whether or not the woman is a carrier. If she is not all offspring would be heterozygous carriers with none of them diseased. If she is a carrier then here is the punnett square  C= normal  c = cfibrosis

       C            c

    c  Cc           cc

    c  Cc           cc