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What is liver glycoprotein and what is its role in humans?

Membrane associated carbohydrate is exclusively in the form of oligosaccharides covalently attached to proteins forming glycoproteins, and to a lesser extent covalently attached to lipid forming the glycolipids. Glycoproteins consist of proteins covalently linked to carbohydrate. The post-translational attachment of carbohydrate to proteins plays a critical role in overall biochemical complexity in humans (as well as all eukaryotes). The importance of this protein modification can be emphasized by the fact that approximately 50% of all proteins are known to be glycosylated and at least 1% of the human genome is represented by glycan biosynthesis genes.

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Advertisement (Bad banner? Please let us know) Share: Cite / link:glycoprotein /gly·co·pro·tein/ (-pro´tēn) a conjugated protein covalently linked to one or more carbohydrate groups; technically those with less than 4 per cent carbohydrate but often expanded to include the mucoproteins and proteoglycans.
glycoprotein [gli″ko-pro´tēn]
any of a class of conjugated proteins consisting of a compound of protein with a carbohydrate group.
α1-acid glycoprotein an acute phase protein found in blood plasma, an indicator of tissue necrosis and inflammation. Called also orosomucoid.
P-glycoprotein a cell-surface protein occurring normally in the colon, small intestine, adrenal glands, kidney, and liver, and also expressed by tumor cells. It is a modulator of multidrug resistance, mediating the transport of antineoplastic agents out of tumor cells.
variable surface glycoprotein any of several glycoproteins that form the antigenic protein coating of Trypanosoma brucei. The organisms contain numerous genes encoding hundreds of such glycoproteins and, by expressing individual ones successively, evade the immune system of the host.
One of a group of conjugated proteins formed by a protein and a carbohydrate, the most important being the mucins (as found in the lens capsule, vitreous humour) and mucoids (as found in bones, cartilage, tendons).


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