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Question
How do fluids or substance leave the vacuole and then leave the cell?

Is is through the CELL MEMBRANE OR THE CYTOPLASM?

Answer
cytoplasm, lined with a membrane, and filled with fluid. Especially in protozoa, vacuoles are cytoplasmic organs (organelles), performing functions such as storage, ingestion, digestion, excretion, and expulsion of excess water. The large central vacuoles often found in plant cells enable them to attain a large size without accumulating the bulk that would make metabolism difficult.

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