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Biology/Sliding Filament Theory Analogy

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Question
Hi,

I'm trying to understand all of the processes of the sliding filament theory - how calcium, actin, myosin, ATP (ADP + P) work together to contract the sarcomere.  Are there any good analogies to understand this theory?

Thank you.

Answer
Dear Jack,

I can't think of any analogies that would encompass all the components of the sliding filament theory.  Which part of it is the hardest to visualize?  The chemical energy component, or just the sliding filaments?  

If it's the sliding filaments, then try to picture two rows of velcro-like fabric with hooks in opposite directions moving against each other.  The hooks will catch in one direction, but move smoothly in the other direction.  In the actin/myosin interaction, the hooks might be said to "relax" so that this can occur in either direction, allowing the sarcomere to either expand or contract, depending on the neurotransmitter signals.

Hope that helps?

Dana

Biology

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Dana Krempels, Ph.D.

Expertise

I can answer biology-related questions in the areas of evolution, zoology, botany, genetics, and ecology. But I don't answer homework questions or provide ideas for your science fair projects. So students please do your learning the right way by reading your text assignments and studying!

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At the University of Miami, I teach Evolution and Biodiversity, Botany, Zoology, Genetics, Ecology, and a variety of seminars (e.g., the Biology and Evolution of Human Gender Roles).

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I have a B.S. in Biology and an A.B. in English from the University of Southern California (1980). I earned my Ph.D. in Biology in the area of evolutionary biology/visual physiology from the University of Miami in 1989.

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I am currently an "expert" in both the "Rabbits" and "Wild Animals" categories.

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