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Biotech & Biomedical/BECKER MUSCULAR DYSTROPHY GENE

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Expert: - 12/1/2008


Question
CAN MUSCULAR DYSTROPHY PEOPLE TAKE CLARITHROMYCIN 500MG BY IV DRIP IF THEY ARE ALLERGIC TO ERYTHROMYCIN - CANT FIND MUSCULAR DYSTROPHY PEOPLE IN THE CLINICAL TRIALS. COULD IT DESTROPY THE DYSTROPHIN GENE AND INCREASE THEIR CPK LEVELS.


Answer
Hi, Lynn,

Short answer - no. Clarithromycin is closely chemically related to erythromycin and almost certainly is cross-reactive - so if you are allergic to erythromycin you will most likely be allergic to clarithromycin as well. Avoid.

Best wishes,

Paul

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Dr.Paul Skett

Expertise

drug metabolism or biotransformation from basic to advanced, hepatocytes from basic to advanced, drug toxicity and side effects, alcohol clearance and levels

Experience

32 years research experience in above areas, 30 years educational experience in University. Retained expert for numerous legal firms dealing with matters of drugs (legal and illegal)and alcohol.

Education/Credentials
B.Sc(Hons) Biochemistry, University of Liverpool, UK
fil.dr. (Medical Chemistry) Karolinska Institute, Stockholm, Sweden

Fellow of the British Pharmacological Society

Fellow of the Higher Education Academy

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