You are here:
Biotech & Biomedical/dichlorovos
Advertisement
Question
hi how would i write equations showing the action of the organophosphorus insecticide dichlorovos with part of the acetylcholinesterase enzyme's active site
thankyou for your time
Hi, Mariam,
Dichlorovos interacts with the serine residue in the active site of acetylcholinesterase at the -OH group. It is a two step process (first one relatively easily reversible, second one not). Base your equation on the serine structure (attached as part of a protein) and work from there.
Hope this helps.
Best wishes,
Paul
- Add to this Answer
- Ask a Question
Questioner's Rating
| Rating(1-10) | Knowledgeability = 10 | Clarity of Response = 10 | Politeness = 10 |
| Comment | No Comment | ||
Related Articles
Biotech & Biomedical
Answers by Expert:
Dr.Paul Skett
Expertise
drug metabolism or biotransformation from basic to advanced, hepatocytes from basic to advanced, drug toxicity and side effects, alcohol clearance and levels
Experience
32 years research experience in above areas, 30 years educational experience in University. Retained expert for numerous legal firms dealing with matters of drugs (legal and illegal)and alcohol.
Education/Credentials
B.Sc(Hons) Biochemistry, University of Liverpool, UK
fil.dr. (Medical Chemistry) Karolinska Institute, Stockholm, Sweden
Fellow of the British Pharmacological Society
Fellow of the Higher Education Academy
©2012 About.com, a part of The New York Times Company. All rights reserved.