Biotech & Biomedical/Important major


computational science or computer-aided drug design, which is more important? Do both need programming?

Hi, Hiam,

Thanks for your question.

The old empirical way of finding new drugs or lead compounds for developing new drugs is long gone - we used to search 1000's of compounds and look at their properties without any real knowledge (other than instinct!!) of what to look for.

Now using rational drug design, scientists can predict what a structure may do and how it can be modified to achieve a better result - molecular graphics gives us the ability to see how a drug needs to fit into its receptor to work. Algorithms can be researched and modified to allow this fitting - the program is only as good as the data put into it!!  These programs are relatively crude still and need a lot more work - many of the designed drugs don't work - why???

So, the answer to your question is yes, these skills are vital and sorely needed - the basic skills of programming and its application to drug design are both needed.

Hope this helps and best of luck with your career in this area.

Best wishes,

Biotech & Biomedical

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Dr.Paul Skett


drug metabolism or biotransformation from basic to advanced, hepatocytes from basic to advanced, drug toxicity and side effects, alcohol clearance and levels


32 years research experience in above areas, 30 years educational experience in University. Retained expert for numerous legal firms dealing with matters of drugs (legal and illegal)and alcohol.

B.Sc(Hons) Biochemistry, University of Liverpool, UK
fil.dr. (Medical Chemistry) Karolinska Institute, Stockholm, Sweden

Fellow of the British Pharmacological Society

Fellow of the Higher Education Academy

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