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Brain Tumors/long term effects - Astrocytoma & radiation

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Question
hello,
my wife who is now in her mid forties had surgery around 1981 for an aggressive astrocytoma ( grade 3). Had course of x6 weeks radium treatment. The surgery and radiation appeared to be successful however whole process took x2 years before she started to recover.  Despite this early trauma in her teens she was able to bear two healthy children  who are now into their late teens.

Unfortunately however she has had major health issues over the last 20 years including seizure activity ( now mostly in remission), loss of peripheral vision, chronic fatigue with at least x3 conversion type disorder episodes ( first thought to be strokes) over the last 4 years. More recently her vision has been steadily deteriorating to the point where she now is reliant on visual aides through the Blind Institute to assist her around  home & ensure she can get around more safely in the community. We would appreciate your comments regarding the role that radiation may have played in these debilitating long term side effects.

Answer
First of all, if this indeed was a grade 3 astrocytoma (correct diagnosis is quite difficult) she has survived remarkably long! This is not impossible though extremely rare! What you describe is not unusual and mostly due to the treated tumour process itself. To evaluate to what extent radiation may play a role here I would need to know 1. The EXACT location of her treated tumour. 2. Her whole radiation therapy treatment plan including dosage schedule. 3. Her brain tumour pathology report would also be of interest. You can copy them here.


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Brain Tumors

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Claes-Gustaf Nordquist, M.D.

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I`m a doctor of medicine and specialist in radiation therapy and medical oncology. I have a long time experience of these tumours.

Experience

I'm a Doctor of Medicine and specialist in Medical Oncology and Radiation Therapy, educated and trained in Sweden. Now retired. Background in Radiation Therapy, Medical Oncology, Radiation Protection, Nuclear Medicine, Diagnostic Radiology, Gynecological Oncology, Clinical Pathology, Clinical Cytology,Hematology and Internal Medicine. M.D. from the faculty of medicine, Royal Karolinska Institute, Stockholm, Sweden. Have also been an exchange student at the Hebrew University, Hadassah Medical School, Jerusalem Israel. Former medical consultant, Swedish National Board of Radiation Protection. Former Police Surgeon and Medical Examiner, Stockholm Police Department. Former Chief Medical Officer, The Royal Guards, The Royal Horse Guards and the Royal Household Brigade, Royal Swedish Army Medical Corps. You can also reach me on: http://www.lifestylerescue.com/expert/health-fitness-advice/dr-claes-gustaf/128 . I have no restrictions on the number of questions there. I also answer questions about Oncology (General Cancer), General History, Military History, Breast Cancer, Colon Cancer.

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Doctor of medicine, specialist in medical oncology & radiation therapy.

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