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About Claes-Gustaf Nordquist, M.D.
Expertise
I`m a doctor of medicine and a specialist in radiation therapy and medical oncology. I have long experience in diagnostics and treatment of breast tumours.

Experience
I'm a Doctor of Medicine. Licensed/certified physician and surgeon and specialist in Medical Oncology and Radiation therapy in Sweden, Denmark, Finland, Iceland, Norway and the European Union. Background in Radiation Therapy, Medical Oncology, Radiation Protection, Nuclear Medicine, Diagnostic Radiology, Gynecological Oncology, Clinical Pathology, Clinical Cytology,Hematology and Internal Medicine. M.D. from the faculty of medicine, Royal Karolinska Institute, Stockholm, Sweden. Have also been an exchange student at the Hebrew University, Hadassah Medical School, Jerusalem Israel. Former medical consultant, Swedish National Board of Radiation Protection. Former Police Surgeon and Medical Examiner, Stockholm Police Department. Former Chief Medical Officer, The Royal Guards, The Royal Horse Guards and the Royal Household Brigade, Royal Swedish Army Medical Corps. Now in private practice in Stockholm, Sweden.

I also answer questions about Oncology (General Cancer), General History, Military History, Brain Tumors, Colon Cancer
 
   

You are here:  Experts > Health/Fitness > Women's Health > Breast Cancer > conflicting biopsy results

Breast Cancer - conflicting biopsy results


Expert: Claes-Gustaf Nordquist, M.D. - 5/16/2008

Question
Hello.  I am 42 years old.  A lobulated mass was found on my first breast screening.  I was told that it was probably benign and to come back in 6 months.  I did that -the mass did not grow, but changed shape - looked even stranger even more lobulated. I decided to get a second opinion at a prestigious breast center.  They saw that it had some irregular borders and increased through transmission, and blood flow within the lesion, they wanted to do a biopsy.  Unfortunately, my insurance said no, and I had to go somewhere else.  Another institution core biopsied it, and it came back benign - a supposed fibroadenoma - Iwas surprised because it had some angular margins.  While giving me the US core biopsy, they found another lump - they did an FNA and the results came back with atypical ductal cells, loosely cohesive groups, prominent nucleoli, singly and mildly overlapping cells, macrophages.  So, they did a vacuum assisted biopsy for definitive results - this too was supposedly another fibroadenoma - however, because of the atypical cells they feel as though they need to surgically remove it to see what's really going on - my breast surgeon also wants to surgically remove the other lobulated mass - just to make sure (it was honestly strange looking to be benign).  So, can you please tell me why I am having so many conflicting results? Atypical cells on FNA and then benign on the US core biopsy of one lump, and then my films showing irregular/somewhat angular and lobulated borders on another mass with benign results from this core biopsy.  What could be the problem?  And, how often are benign core biopsy results wrong?

Answer
Both core and FNA biopsies are usually VERY reliable - in trained hands. But of course mishaps are not completely unknown. Here we are dealing with 2 different lesions too. I have no other explanation at present. I do agree that surgical biopsies of both lesions should be done in this situation!


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