Breast Cancer/IHC Test result

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Expert: - 11/28/2009


Question
Hi,

My mother recently underwent modified radical mastectomy of right breast after being diagonosed with Infiltrating Duct Carcinoma, Grade II (NBR Score 7)  This was followed by a IHC test whose results showed as mentioned :

1) Estrogen Receptor (ER) Score 2/8 Negative
2) Progestrone Receptor (PR) Score 2/8 Negative
3) Her-2neu )c-erb B2) " Score-0 Result Negative.

What does this mean ?

Thanks in advance for your kind response.

Regards
Somnath  

Answer
She has been treated for a breast cancer of medium malignancy originating in the inner lining of a milk duct. The tumour does not have any hormone receptors so any hormonal treatment of this is meaningless. Also there is no sign of any Her-2 which is good for such cancers are more aggressive. But of course I can not give you any guarantees!

I have some computer problems so unfortunately my reply is delayed.

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Breast Cancer

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Claes-Gustaf Nordquist, M.D.

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I`m a doctor of medicine and a specialist in radiation therapy and medical oncology. I have long experience in diagnostics and treatment of breast tumours.

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I'm a Doctor of Medicine and specialist in Medical Oncology and Radiation Therapy educated & trained in Sweden. Now retired. Background in Radiation Therapy, Medical Oncology, Radiation Protection, Nuclear Medicine, Diagnostic Radiology, Gynecological Oncology, Clinical Pathology, Clinical Cytology,Hematology and Internal Medicine. M.D. from the faculty of medicine, Royal Karolinska Institute, Stockholm, Sweden. Have also been an exchange student at the Hebrew University, Hadassah Medical School, Jerusalem Israel. Former medical consultant, Swedish National Board of Radiation Protection. Former Police Surgeon and Medical Examiner, Stockholm Police Department. Former Chief Medical Officer, The Royal Guards, The Royal Horse Guards and the Royal Household Brigade, Royal Swedish Army Medical Corps.You can also reach me on: http://www.lifestylerescue.com/expert/health-fitness-advice/dr-claes-gustaf/128 I have no restrictions on the number of questions there.

I also answer questions about Oncology (General Cancer), General History, Military History, Brain Tumors, Colon Cancer

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I'm a medical doctor and specialist in medical oncology and radiation therapy.

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