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Colon Cancer/Stage iv signet cell colon cancer

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QUESTION: My husband just had surgery today for colon cancer and the surgeon gave me the unexpected news that he is very advanced and the outlook is very bad. He has stage iv signet cell colon cancer with peritoneal seeding throughout the abdomen. He is 48 and otherwise relatively healthy although he is now the 3rd generation to have colon cancer (his father and grandfather).  We have three children... Aged 9, 12 and 15. Is there truly no hope? How long can chemo prolong his life?
Thank you

ANSWER: Signet cell colon cancers are usually more aggressive than the common variety. The way his cancer is growing as you have described it supports this condition. A stage 4 colon cancer - it's stage is supported by the observed findings you describe - is at present not curable and eventually fatal. However with chemotherapy the survival time MAY be extended. The longest periods I know of with colon cancer and chemotherapy are around or a little more than 6 years. It is doubtful however if any of those was a signet cell cancer. So here the time may be shorter. On the other hand chemotherapy develops all the time and results are getting better. So it is impossible for me to estimate with any certainty the probable survival time of your husband. And besides no result can be guaranteed. We can but try and hope for the best! I am sorry I can not provide a sure or better answer!




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---------- FOLLOW-UP ----------

QUESTION: Thank you for the compassionate reply.

My husband's surgeon has recommended aggressive chemotherapy for 6-9 months (12 rounds) and a HIPEC procedure after that. I've been unable to find information on HIPEC success rates, only information that describes the procedure, and where it is performed.  We live in the northeast USA and are considering Sloan-Kettering in NY and Tufts Medical in Boston.

thank you once again for your time.

Answer
I think you have been given good advice and both these centers have a good reputation! Good luck!




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Colon Cancer

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Claes-Gustaf Nordquist, M.D.

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I`m a doctor of medicine and a specialist in radiation therapy and medical oncology. I have long experience with regards to this cancer.

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I'm a Doctor of Medicine and specialist in Medical Oncology and Radiation Therapy educated & trained in Sweden. Now retired. Background in Radiation Therapy, Medical Oncology, Radiation Protection, Nuclear Medicine, Diagnostic Radiology, Gynecological Oncology, Clinical Pathology, Clinical Cytology,Hematology and Internal Medicine. M.D. from the faculty of medicine, Royal Karolinska Institute, Stockholm, Sweden. Have also been an exchange student at the Hebrew University, Hadassah Medical School, Jerusalem Israel. Former medical consultant, Swedish National Board of Radiation Protection. Former Police Surgeon and Medical Examiner, Stockholm Police Department. Former Chief Medical Officer, The Royal Guards, The Royal Horse Guards and the Royal Household Brigade, Royal Swedish Army Medical Corps. You can also reach me on: http://www.lifestylerescue.com/expert/health-fitness-advice/dr-claes-gustaf/128 I have no restrictions on the number of questions there.

I also answer questions in these categories: Oncology (General Cancer), General History, Military History, Brain Tumors, Breast Cancer.

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I'm a medical doctor and a specialist in medical oncology & radiation therapy.

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