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I bought 6 female bettas a week ago. Almost immediately i noticed one had very clamped fins and stayed near the top in a corner. She would sometimes freak out and "shiver" and dart and scrape herself on objects. I figured this sounded like gill flukes; or some sort of parasite for sure, though nothing visible. She also has faint white-ish patches on her head that i can only see in the light at certain angles, kind of like excess slime coat, but in patches. Maybe fungal or bacterial? Or in response to parasite irritation?
I put her in a 2.5 gallon hospital tank (with another submissive female for company and so she wouldn't get used to being alone), and put in 1 tsp/5 gal of aquarium salt, and started treating with Tetra's Parasite Guard, a combo of Praziquantel, Dflubenzuron, Metronidazole and Acriflavin, since i'm not sure what parasite i'm dealing with.
The instructions say to dose every two days after a water change. Today was her third dose, so her fifth day on the meds (i'm doing 100% water changes every two days before re-dosing).
She seems as bad as ever. Hardly swims at all, just hangs at the top or lays on the bottom, almost on her side sometimes. Her fins are very pinched, and she is pale with horizontal stripes. If i wake her up once a day to see if she is still alive she freaks out and shakes and flashes everywhere and stretches her gills open. The other girl in there with her in ok, and doesn't bother her at all.
I've read that flukes can be really irritating before finally dying. But i'm just wondering, how long is this suppose to take? When will she start getting better? I don't want her to die! Should i do something else? I didn't think it should be taking this long.
(Since they all came in the same batch and some of the other girls also had clamped fins, i'm also treating the big tank with the same meds. None of them are getting worse, so i hope it's working for them, though some still have clamped fins sometimes. Even the pleco is fine, so the meds can't be that hard on them. But then, is it strong enough to kill the parasites? If i have to start a different treatment in the hospital tank, should i also in the big tank?)
Please tell me what to do! Should i wait some more? Add something to the treatment? Try something else intirely? How long until the fluke life cycle is completelly ended?

(Also i have large drift wood in the big tank. Does that affect the meds in any way? Does it absorb it, leaving less in the water to treat the fish? There is none in the hosital tank. But i didn't want to treat with something that would stain the wood. But if i have to take it out i will.)
Thank you!

Answer
Hi Joleen,
 Hmmm.. that is a tough.  First, because you have a catfish in the big tank be very careful about any meds you put in there; catfish are extremely sensitive to medications.

  There is not set time that it takes a medication to cure a disease.  The reason is that in some cases the disease keeps reinfecting and it may take a while to competely get rid of it.  This is particularly true of parasites that have complex multistage life cycles (such as ich and many flukes).

Personally, I would not have that other fish in the hospital tank. You risk it getting infected. She does not need company and in fact, "company" may contribute to her illness.  

Bottom line: I would isolate the sick fish and keep treating her.

-- Ron Coleman
  rcoleman@cichlidresearch.com
  Cichlid Research Home Page <http://cichlidresearch.com>  

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Ron Coleman

Expertise

I am an expert on cichlid fishes, particularly New World cichlids. My broader expertise includes the behavior, ecology and reproduction of fishes in general. (I am NOT an expert on Goldfish). Please do not use abbreviations, such as "my GT has a swollen eye" because I don't know what a "GT" is. The more clearly you can explain your question, the better chance I have of understanding what it is that you seek. I keep fishes both as a scientist and as a hobbyist and I currently maintain about 140 aquariums.

Experience

I am an Associate Professor at the California State University, Sacramento in the Department of Biological Sciences, and I run a website, called the Cichlid Research Home Page . I also write for many popular aquarist magazines, and I was editor of Cichlid News magazine for several years. I am a scientist and I spend my time teaching fish biology, ecology, behavior and evolution and doing research on the reproductive biology of fishes, particularly cichlids. I do research in the laboratory and in Costa Rica, Nicaragua and Mexico. My main interest is understanding the evolution of parental care in fishes. I am interested in encouraging greater public awareness, understanding and participation in science.

Publications
Cichlid News, Tropical Fish Hobbyist, Freshwater and Marine Aquarium, Science, Behavioural Ecology and Sociobiology, Copeia, Canadian Journal of Zoology, Trends in Ecology and Evolution, AUK, Environmental Biology of Fishes

Education/Credentials
PhD (Toronto, 1993) MSc (Simon Fraser, 1986) BSc (British Columbia, 1983)

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