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About danil hammoudi.md
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general surgery , expert several web site, president of sinoe medical association, answer more than 2000 a month , everybody satisfied

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10 years general surgery

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You are here:  Experts > Health/Fitness > Medical Specialists > Gastroenterology > gastroparesis and bezores

Gastroenterology - gastroparesis and bezores


Expert: danil hammoudi.md - 8/22/2004

Question
I have recently been diagnosed with delayed gastric emptying, by two capsule endoscopy studies.  I just read about the recommended diet, and I have been eating all the wrong things!  I figured fiber would be good, but obviously dried apricots are out!  My pain has been increasing, and I wonder  how you know if you have a bezore?  What is the treatment for it and can I do anything to help myself at home?  I wish my Dr. had explained this, but all I got was a referral to the Motility Specialist in another 3 weeks.  Thank you

Answer
1/ are you diabetic?
2/ do you eat hair , meaning do you put hair in your mouth?
I think you are talking about bezoar, which often is a hair ball but can other constituants in the stomach and the treatment is surgical if to big

Bezoar is a mass of compacted material such as food, hair and vegetable material that collects in the gastrointestinal tract, usually the stomach. This may result from impaired emptying of the stomach. Common causes of impaired emptying include:

Surgery on the stomach nerve (vagus) or distal stomach
Diabetic nerve damage (neuropathy), which can cause paralysis of the stomach (gastroparesis)
Stomach outlet obstruction, such as due to scarring from peptic ulcers
People who compulsively pull out their own hair (trichotillomania) and eat it also may get bezoars.

Bezoars typically consist of plant materials and hair. But they may also consist of fiber supplements, drugs such as sucralfate (Carafate), and even paper. Signs and symptoms of bezoar are:

Feeling full after eating only a small amount
Nausea
Vomiting
Upper abdominal pain
A doctor may diagnose bezoar by barium X-ray or endoscopy of the upper gastrointestinal tract. In endoscopy, the doctor places a thin, flexible instrument attached to a camera through your mouth into your stomach. Treatment depends on the content and location of the bezoar. Treatment may include disrupting — which allows you to pass it — or removing the bezoar using an endoscope or suction (lavage) tube. Surgery may be needed.

Once you've had one bezoar, you're more likely to have another unless:


The underlying emptying problem can be successfully treated
You reduce or eliminate consumption of the insoluble material causing the bezoar

Gastroparesis is the failure of the stomach to empty because of decreased gastric motility. Normally, your stomach contracts slowly to squeeze solid food into small particles. Your stomach pushes these compressed solids and liquids into the small bowel. With gastroparesis, the stomach is paralyzed, so its function is greatly reduced or lost. Because the stomach isn't moving the food into the small bowel, it stays in the stomach longer than normal.
Gastroparesis is one of the common gastrointestinal complications of diabetes. People with scleroderma, those on anticholinergic medications commonly used for treatment of conditions such as asthma and Parkinson's disease, and those who have had surgery (vagotomy) for treatment of a duodenal ulcer may also suffer from gastroparesis.

The major causes are diabetes, vagotomy, gastric resection, and use of anticholinergic medications.  For most patients the cause is unknown
Typical symptoms of gastroparesis include nausea, frequent and uncontrollable vomiting, abdominal bloating, feeling of immediate fullness upon eating, and loss of appetite. In patients with diabetes, frequent vomiting can cause dehydration, which can lead to diabetic ketoacidosis, a toxic build-up of chemical compounds in the blood that can lead to coma in patients with diabetes. Prolonged vomiting can also make the lining of the stomach bleed. Vomiting usually occurs after meals. People with gastroparesis usually vomit undigested food eaten anywhere from 8 to 24 hours earlier. Some patients experience days of nausea, bloating, and little appetite, but no vomiting.

How is it diagnosed?
To accurately diagnose gastroparesis, your doctor may order tests that include an upper-gastrointestinal (GI) series of x-rays or a gastroscopy (gastricemptying study), which allows the doctor to look into the stomach with a scope to measure the ability of your stomach to empty food.

Treatments for gastroparesis include eating small meals throughout the day and avoiding fatty foods and other foods that are difficult to digest, such as legumes, lentils, and citrus fruits. If you have gastroparesis as a complication of diabetes, you may need to intensify insulin therapy to get better control of your blood glucose. A number of drug therapies are also used to treat gastroparesis. The most effective is metoclopramide, which helps the stomach to empty by stimulating stomach activity. It may also relieve nausea and vomiting. Common side effects include drowsiness and fatigue. Some people may also experience depression, movement disorders, anxiety, and breast tenderness or discharge. Metoclopramide is not recommended for patients with Parkinson's disease. While the antibiotic erythromycin improves stomach emptying, its side effects of nausea, vomiting, and abdominal cramps limit its usefulness. One additional drug, domperidone, is not yet approved for use in the U.S., but is under review by the FDA. Domperidone improves stomach emptying by stimulating stomach motor activity, relieves nausea, and has few side effects. If drugs do not work for you, your physician may recommend a jejunostomy tube, which allows food to bypass your stomach. Liquid nutrition, fluids, and medication are delivered directly to the small bowel through the tube during severe attacks of gastroparesis. In extremely severe cases of gastroparesis, patients may need a semi-permanent intravenous line that delivers nutrients and fluids directly into the bloodstream.

overall the causes :Major causes of gastroparesis


Diabetes
Postviral (after a virus) syndromes
Anorexia nervosa
Surgery on the stomach or vagus nerve
Medications, particularly anticholinergics and narcotics (drugs that slow contractions in the intestine)
Gastroesophageal reflux disease (rarely)
Smooth muscle disorders, such as amyloidosis and scleroderma
Nervous system diseases, including abdominal migraine, and Parkinson's disease
Metabolic disorders, including hypothyroidism

So these need to be check in the same time that you start treatment.

hope this answers your question
thanks

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