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Genetics/Engineered mother's milk

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Question
Hello Mr. Thanemozhi Natarajan,

I was listening to NPR's Fresh Air the other day.  

http://www.npr.org/2013/03/11/173514863/frankensteins-cat-bioengineering-the-ani

To topic was genetic engineering.  One of the topics was using a genetically modified goat to produce a human protein (lysizine?).  From the way it was described this is naturally produced in protein mothers milk and it is a great anti-biotic. This genetically modified goat will now be able to produce this with its own milk.

I am a bit scared about this.  With the way that bacteria is overcoming resistant with our current antibiotics, what is to prevent this from happening to this Lysizine protein?  

If this were to occur wouldn't this be potentially devastating to the lives of many babies?

Thanks,

Allen

Answer
Allen,

You thinking is not off the track. Just as microbes can attain resistance over naturally produced  proteins/antibodies, there is nothing special about this protein to not render microbes resistant. Only a long term monitoring of this protein metabolism and it's mechanism of action against bacteria can tell us whether it would be devastating, neutral or harmless.

T

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Thanemozhi Natarajan

Expertise

Answers in Genetics, genomics, cytogenetics of syndromes, congenital anomalies, cancer, clinical genomics and interpretation of omics data.

Experience

More than 10 years. Doctoral research thesis on Congenital anomalies and cytogenetics, Recurrent reproductive failure and chromosomal abnormalities. Postdoctoral experience in Breast cancer research. Current: Clinical Genomics and Pharmacogenomics.

Organizations
Academic

Publications
Cancer Cell International, Cancer Epidemiology Biomarkers and Prevention, Breast cancer research and treatment, Indian Journal of Pediatrics, BMC Proceedings, Pharmacogenetics and Genomics, Human Molecular Genetics, Frontiers in Genetics, Cancer Biomarkers.

Education/Credentials
PhD Biomedical Genetics

Awards and Honors
University Grants Commission Award for pursuing PhD level research (India); Travel awards to attend conferences.

Past/Present Clients
Post doctoral experience Cancer research, molecular epidemiology Current: Clininical Genomics and Pharmacogenomics

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