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Genetics/adaptive mutation



I read that adaptive mutation help increase the chances of survival of orgnaisms. What is the mechanism that the information regarding survival of organism gets transferred to the genes. In other words, if a particular mutation have helped the organism to enhance their survival, how does it get into the genes? What force/entity makes it to incorporate into the genes?  Does the genetic information increase due to adaptive mutation?



Hi Ameen,

Adaptive mutations, as the name implies means 1) It is already integrated to the genes and 2) It aids the animal to survive in some manner-a particular environment.
Genetic material is flexible and not all of us have the same "code" - so it is in all life forms- plants or animals. There are minor modifications happening all the time that wont put the animal at any disadvantage- let us call it neutral. However, these minor modifications, scientifically called polymorphisms, can lie "low" for generations. But when suddenly environment changes, these mutations can suddenly come handy and their function can tremendously boost the survival power of the animal/plant. Once these "now favorable" mutations are in action, the offsprings of these animals/plants will continue to enjoy it and flourish, while the other members of the species will perish in the new environment. This is how adaptive mutations get "integrated" collectively into the genome of a surviving group of species community.  These kinds of mutations constantly occur within the genome of all species of life. Just like good mutations prevail, bad mutations also occur and depending on the fatality, the organism may die in womb, or in early life or adult life. These members of the species do not get to mate or propagate their gene package and they are weeded out of the species.




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Thanemozhi Natarajan


Answers in Genetics, genomics, cytogenetics of syndromes, congenital anomalies, cancer, clinical genomics and interpretation of omics data.


More than 10 years. Doctoral research thesis on Congenital anomalies and cytogenetics, Recurrent reproductive failure and chromosomal abnormalities. Postdoctoral experience in Breast cancer research. Current: Clinical Genomics and Pharmacogenomics.


Cancer Cell International, Cancer Epidemiology Biomarkers and Prevention, Breast cancer research and treatment, Indian Journal of Pediatrics, BMC Proceedings, Pharmacogenetics and Genomics, Human Molecular Genetics, Frontiers in Genetics, Cancer Biomarkers.

PhD Biomedical Genetics

Awards and Honors
University Grants Commission Award for pursuing PhD level research (India); Travel awards to attend conferences.

Past/Present Clients
Post doctoral experience Cancer research, molecular epidemiology Current: Clininical Genomics and Pharmacogenomics

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