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About Peter J. Panagotacos, <B>M.D.</B>
Expertise
I have 30 years experience in the field of medical and surgical Hair Restoration and am Board Certified in Dermatology and Hair Restoration Surgery.

Experience
I have 30 years experience in the field of medical and surgical Hair Restoration and am Board Certified in Dermatology and Hair Restoration Surgery. More information can be found at my website www.hairdoc.com
 
   

You are here:  Experts > Health/Fitness > Men's Health > Hair Loss > Hair Loss When Stopped Taking Spironolactone

Topic: Hair Loss



Expert: Peter J. Panagotacos, <B>M.D.</B>
Date: 9/3/2007
Subject: Hair Loss When Stopped Taking Spironolactone

Question
Hi Dr. Penagotacos,

I have been on spironolactone 50 mg/day for about 6 years for Acne/PCOS.  I never had a problem with hair loss.  About 18 months ago I got a generic brand that gave me horrible side effects so I reduced my dose to practically nothing.  Within weeks I was losing all my hair.  I went back on ever-increasing dosages first 50, then 100, 150, now 200 mg/day on the advise of a reproductive endocrinologist.  I am still going bald.  

Can stopping the drug cause a reverse effect?  What should I do now?  I'm afraid to go off of it in case the shedding becomes even worse.  In 18 months I have lost 1/3 - 1/2 of the hair on my head and sprouted new hairs over 100% of my body, including my face.

I am desperate.

Thanks,

Pam  

Answer
You are sprouting hair because your testosterone level is too high giving you a high DHT. In order to prevent this taking 200mg of spironolactone is a standard dose. but in some patients it may not be enough. You have not mentioned what oral contraceptive pill you are on. I would suggest Ortho Tri Cyclen. If you are on a mini pill that could be the problem. Lastly why not ask your endocrinologist if you could take Avodart- Dutasteride. It is not usually given to women since it is meant to treat Prostate problems in men but it is the only medicine out there that will block 5-alpha reductase Type I which is in the skin and hair of men and women. This blocks production of DHT so that even if you have an elevated testosterone you will have fewer hairs to growing on your body and less baldness because the DHT that causes that.

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