AboutWilliam B. Jeffries, Ph.D. Expertise Questions on the mechanism of action and side effects of antihypertensive drugs, the epidemiology of hypertension and the cardiovascular complications of untreated or undertreated high blood pressure
Experience I have been an investigator in the field of hypertension research for over 20 years.
Organizations Council for High Blood Pressure Research
American Society for Pharmacology and Experimental Therapeutics
American Heart Association
Publications Hypertension, Journal of Hypertension, Journal of Pharmacology and Experimental Therapeutics, Molecular Pharmacology, American Journal of Physiology, Pharmacology and Therapeutics of Dentistry
Question My VA doctor prescribed .5mg of Lisinopril once dailty about a month ago. I take flunisolide .25% twoce dai;y -upon rising & when going to bed for allergies. Now I have throughout the day a dri into my throat that is worse when I lay down to get to sleep. I cough up the drip fluid constantly & more severely when I lay down for about 15 minutes. Naturally it disturbs my sleep pattern which has always been good. Is there an interaction bwtweenthe two drugs? The allergy medicine controlled the drip in the past but not now. Your advice would be
most appreciated.
Thank you,
Robert
Answer I do not know of a specific interaction between these two drugs. However, it is well known that lisinopril and other members of its class can cause a persistent cough. This condition should promptly be brought to the attention of your doctor (call today), who will want to evaluate the source of your symptoms. If it determined to be due to lisinopril, you will likely be switched to a drug from another antihypertensive class.
