AboutWilliam B. Jeffries, Ph.D. Expertise Questions on the mechanism of action and side effects of antihypertensive drugs, the epidemiology of hypertension and the cardiovascular complications of untreated or undertreated high blood pressure
Experience I have been an investigator in the field of hypertension research for over 20 years.
Organizations Council for High Blood Pressure Research
American Society for Pharmacology and Experimental Therapeutics
American Heart Association
Publications Hypertension, Journal of Hypertension, Journal of Pharmacology and Experimental Therapeutics, Molecular Pharmacology, American Journal of Physiology, Pharmacology and Therapeutics of Dentistry
Question My husband has been taking this medication fot 2 weeks and he says he is very depressed, no energy, and feels weak-is depression a side effect of this medication? I have noticed he has not acted like himself. Thank you.
Answer Lisinopril is not known to cause clinical depression. However, a small number of patients have reported the symptom of "low energy." Perhaps your husband falls into this category. If it were me, I would discuss this with the prescribing physician and determine if lisinopril is the still the best choice for an antihypertensive drug.
