Dear Dr. Ramirez,

On Feb 14, day 1 of my cycle,  I started a medicated cycle of FET.  Two blastocysts were transferred on March 4 and I tested positive for pregnancy 2 weeks later.   Also starting March 4, my doctor gave me prednisolone 5mg to be taken 2 tablets twice daily (20mg per day).  On April 9 (5 weeks on the drug), I will start to taper off on the  Prednisolone.  I would like to seek your expert advise on the proper way to taper it off.  My doctor told me to reduce the dose by half (10mg daily) and take it for 2 weeks then stop.  Does that sound about right?  

Thank you so very much for your help.

Hello Susan from Hong Kong,

Your doctor's protocol is okay.  I don't think you have to go 2 weeks, 1 week would be enough after tapering but 2 weeks works fine for me if that is his protocol.

Good Luck,

Dr. Edward J. Ramirez, M.D., FACOG
Executive Medical Director
The Fertility and Gynecology Center
Monterey Bay IVF Program

Monterey, California, U.S.A.

for additional information check out my blog at check me out on twitter with me at @montereybayivf and facebook @montereybayivf.  Skype and internet comprehensive consultations now available via my website for those who want a more extensive evaluation that this site can accommodate.  I also now provide an Email Concierge Advisory Service with a 1 year subscription for patients that want easy access to me to answer questions along their journey (women's health, infertility, pregnancy).  Contact me at if you are interested in continuous access to me.


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Edward Joseph Ramirez, MD, FACOG


I am a specialist in infertility and advanced gynecological care. I can answer questions about infertility, gynecology related ills, menopause...virtually anything that affects women's health. PLEASE tell me where you are writing from as I am always interested.


I have been practicing as an Ob/Gyn and Infertility Specialist for over 23 years. Gynecology, advanced laparoscopic surgery, basic infertility, IUI's, IVF, reproductive surgery, and ovulation induction are all areas of my expertise. I am Board Certified. I have been doing In Vitro Fertilization in my clinic for 19 years.

American College of OB/GYN, American Board of Obstetrics and Gynecology, American Society of Reproductive Medicine, California Medical Association, American Association of Gynecologic Laparoscopists, Fellow of The American College of Obstetricians & Gynecologists

American Journal of Obstetrics and Gynecology, Wall Street Journal, Monterey Herald, SERMO, Women's Health and Fertility Blog

Medical Degree from Stanford University, Residency at Tripler Army Medical Center, Reproductive Training at Pacific Fertility Center, San Francisco

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