AboutScott Roseff, MD, FACOG Expertise I can answer questions relating to ALL aspects of female infertility.
Experience I am Board Certified in Reproductive Endocrinology/Infertility.
Organizations Medical Advisory Board, Serono Labs, Inc.
Speaker's Bureau, TAP Pharmaceuticals, Inc.
The American Society for Reproductive Medicine
American Association of Gynecologic Laparoscopists
The International Society for Gynecologic Endoscopy
The Society of Laparoendoscopic Surgeons
The International Federation of Gynaecologic Endoscopists
U.S. International Foundation for Studies in Human Reproduction, Inc.
The Endometriosis Association
Fellow, The American College of Obstetricians & Gynecologists
American Medical Association
The Academy of Medicine of NJ
NJ Obstetrical & Gynecological Society
The NY Reproductive Medicine Society (Steering Committee)
The Society of Reproductive Endocrinologists
Resolve - National Chapter
Resolve - New Jersey - Executive Board
Publications Kettel LM, Roseff SJ, Berga SL, Mortola JF, Yen SSC. Hypothalamic-pituitary-ovarian response to clomiphene citrate in women with polycystic ovary syndrome. Fertil Steril. 1993;59:532-8.
Fischer UG, Wood SH, Bruhn J, Roseff SJ, Mortola JF, Rivier JE, Yen SSC. Effect of human corticotropin-releasing hormone on gonadotropin secretion in cycling and postmenopausal women. Fertil Steril. 1992;58:1108-12.
Kettel LM, Roseff SJ, Bangah M, Burger HG, Yen SSC. Circulating levels of inhibin in pregnant women at term: simultaneous disappearance with oestradiol and progesterone after delivery. Clin Endocrinol. 1991;34:19-23.
Kettel LM, Roseff SJ, Chiu TC, Bangah ML, Vale W, Rivier J, Burger HG, Yen SSC. Follicular arrest during the midfollicular phase of the menstrual cycle: a gonadotropin-releasing hormone antagonist imposed follicular-follicular transition. J Clin Endocrinol Metab. 1991;73:644-9.
Roseff SJ, Kettel LM, Ulmann A, Bangah ML, Rivier J, Burger HG, Baulieu E, Vale W, Yen SSC. Accelerated dissolution of luteal-endometrial integrity by the administration of antagonists of gonadotropin-releasing hormone and progesterone to late-luteal phase women. Fertil Steril. 1990;54:805-10.
Roseff SJ, Murphy AA. Laparoscopy in the diagnosis and therapy of chronic pelvic pain. In Clinical Obstetrics and Gynecology. JB Lippincott Co., Philadelphia. 1990.
Roseff SJ, Murphy AA. Pelviscopy. In Manual of Endoscopy, by the American Association of Gynecologic Laparoscopists, Edited by DC Martin, GL Holtz, M Wenof. Santa Fe Springs. 1989.
Roseff SJ, Bangah M, Kettel LM, Vale W, Rivier J, Burger HG, Yen SSC. Dynamic changes in circulating inhibin levels during the luteal-follicular transition of the human menstrual cycle. J Clin Endocrinol Metab. 1989;69:1033-9.
Roseff SJ, Bernard JM. Seasonal changes in carbohydrate levels in tissues of Carex lacustris. Can. J. Bot. 1979; 57:2140-44.
Education/Credentials Postgraduate Fellowship training in Reproductive Endocrinology & Infertility was done at The University of California, San Diego, School of Medicine.
Awards and Honors Mellon Fellow in Reproductive Endocrinology and Infertility, 1988, awarded for academic excellence in the Reproductive Sciences, for research efforts aimed at development of novel contraceptives.
Wyeth Service Award for Physician Education and Training in Norplant Contraceptive Implants.
Certificates of Service and Appreciation from Our Lady of Mercy Medical Clinic, Guadalajara, Jalisco, México, 1978-1982.
Question I am 26 years old without major health problems diagnosed with infertlity in May due to anovulation. All of my fertility hormones were normal although my testosterone was high normal. I was started in clomid 50mg without ovulation then 100mg with a successful pregnancy which resulted in a miscarriage at 7 weeks. I had to take provera to resume my periods after it did not show for 7 weeks. This past month was my second round of clomid at 100mg. On cycle day 23 my progesterone level was 10! (This is the same as it was when I conceived.) But I did not get pregnant this time. Why could this be? Should I even waste my time doing another cycle? Is there a cap on the number of time one could use clomid? Was it too soon after my miscarriage to try again? I am looking for an explanation any information you can provide to me will be helpful.
Also I have read a few things about an herb called vitex. Can you tell me what you think about this herb?
Answer Hi Kim,
Sorry to hear about your loss :(
To answer:
Why could this be?
==> If everything is "perfect", it doesn't guarantee you will conceive on Clomid that cycle.
Should I even waste my time doing another cycle?
==> Since you're not my patient, I can't tell you if you should continue on your present course or not. The only way I could tell you would be after a consultation here and review of your records. You're certainly welcome to do so.
Is there a cap on the number of time one could use clomid?
==> Most women conceive within an average of 3-4 cycles. Also, we "cap it out" after about 6 cycles or so, due to the report about increased ovarian cancer rates in women who took Clomid for prolonged periods of time (which I'm sure your doctor discussed with you).
Was it too soon after my miscarriage to try again?
==> I have my patients wait at least a month after miscarriage to try again.
Given the fact that you're not ovulating regularly, along with the fact that you lost your pregnancy, I HIGHLY recommend you seek the advice and care of a qualified reproductive endocrinologist. Again, you're welcome to do so here.
Dr. Roseff, Director WECARE in NJ
Visit us at www.reproendo.com
