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Lupus/Antibody levels for Lupus.


I have a positive ANA  SM antibodies, SSA (Ro) antibodies, SSB (La) antibodies, Ro52 antibodies, Jo-1 antibodies, Sci-70 antibodies and Ribsonal P antibodies.  My ENA is negative.    I suffer from symptoms of lupus but a doctor said I do not have it, that he thought I had fybromyalgia. I am puzzled as I thought the SM antibody alone was a pointer for lupus, as the level is minus 1, therefore if you have any SM antibodies at all you have lupus.   I have been in that much pain I really would like to find an answer.  Thank you.

Hello Gay-
I know how frustrating it is to try to get a diagnosis so you can move forward. It took me 2 years and multiple doctors (and a desperate plea to God) to finally get diagnosed with lupus.

Last I knew there was no one specific test that meant you had lupus. That is what makes it so hard to diagnose, although an positive ANA is one possible sign of lupus. It's diagnosed at the discretion of the doctor using a combination of lab tests and symptoms. You may find this webpage on diagnosing lupus to be very helpful:

Lupus pain and fibromyalgia pain, in my experience (I have both) are different. For me, lupus causes joint pain and swelling and nerve pain (burning and tingling), whereas the fibro causes muscle pain and tenderness without joint swelling.

You might also consider getting a second opinion.

Finally, I encourage you to have a look at this page on reducing autoimmune activity naturally, as well, because whatever is going on with you, you definitely have something autoimmune happening:

All my best wishes-

Carla Ulbrich

The Singing Patient: Author, Survivor, Humorous Songwriter and Entertainer - Carla's book "How Can You NOT Laugh at a Time Like This?"


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Carla Ulbrich


I can answer questions such as "what is lupus?" (How common is it? Is it contagious? What are the symptoms? etc.). Also, I can answer questions such as "what are the available treatments for lupus?" (both standard and alternative). Really, I'll take almost any question on lupus, though. If I can't answer it, I'll be very surprised, but I'll also go find someone who can.


I've been living with lupus (SLE) since 1992. I've had three severe bouts with it, including symptoms such as kidney failure and stroke (if you can call having a stroke a "symptom"). I have completely regained my health, though I have to be mindful to take care of myself, lest I get sick again. I use both mainstream and alternative medicine, and have tried just about everything under the sun to alleviate symptoms. A lot of it worked.

Lupus Foundation of America Association for Applied and Therapeutic Humor Toastmasters Folk Alliance

How Can You Not Laugh at a Time Like This? (Tell Me Press, pub.) What is Laughter Lupus Sundial Newsletter

BA in music (UNC-Greensboro)

Awards and Honors
Novelty Song of the Year, Just Plain Folk Awards Winner, South Florida Folk Festival Song Competition Lupus Foundation of America Seal of Approval (for book)

Past/Present Clients
Medicaid Conference Alaska Palliative Care Conference Right at Home Health Care SePHIMA Anritsu Club Med Nursing in Practice

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