About Meir Wetzler <B>M. D.</B> Expertise Leukemia acute and chronic; from chemotherapy to transplantation. Done clinical and translational research on leukemia for the last 10 years at the Roswell Park Cancer Institute.
Question "My twin daughters were diagnosed with infantile ALL when the were 7 weeks old. Both have followed relevant protocols but unfortunately we lost one of them 10 days after her BMT at 6 months old due to renal failure and VOD. Her sister is 2 years old now and 18 months post BMT and recently has been unwell, lethargic at times, occasional vomiting, intermittent temperatures and eating much less. She is 2 years old but undersized due to chemotherapy. Her blood results revealed a high platelet count of 465, and a white cell count of 34.00, neutrophils raised to 27.20. Liver function looks normal. To date no source of viral or bacterial infection has been found and we are due to go back to the hospital next week for full work-up, in the mean time I'm going crazy....any ideas??"
Answer Dear Cathy,
I'm sorry to hear about your daughters. Concerning the elevated white blood cell and platelet counts, those seem to be reactive and the possibility of an infection that will present itself with additional testing is still high. Are there any new medications that your daughter was started on? Also, do you know who the donor was and how well the donor is doing?
Thx, Meir.
