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Oncology (General Cancer)/shall appreciate your valuable advise.-ANAPLASTIC CARCINOMA OF LUNG


medical reports of kanagalatha
medical reports of kan  

Biopsy and IHC  report
Biopsy and IHC report  
Dear Dr,

Shall appreciate if you would kindly let us know the best course of management of the following patient who is my mother in law Mrs.Kanagalatha.

Brief history:76 yr old tee totaller vegetarian,IHD on clopidogel.

Diagnosed to have anaplastic carcinoma stage 3 rt upperlobe with no regional lymph node involvement-underwent Rt upper lobectomy with  mediastinal lymph node resection at chennai and has been discharged and recovering well .Pre op PET scan revealed no metastasis.

Post op:Biopsy at chennai revealed:cytokeratin postitive,TTF -Positive few cells-poorly differentiated anaplastic carcinoma of pulmobnary origin.

Post op biopy -2nd opinion of the wax block at Tata Memorial Institute revealed.High grade malignant epitheloid tumor suggest  Pleomorphic carcinoma.

(Detailed biopsy and medical  reports extracts enclosed herewith.)

Shall be obliged if you would kindly give your valuable opinion on further management and prognosis.


Thanks! This is a poorly differentiated high grade lung cancer with a very bad prognoses based on experience even if at present no metastases have been found. Even so their presence even if not yet detectable is very probable! I therefore do suggest postoperative chemotherapy. Since I do not know what is available where you are I will not suggest any specific chemotherapy combination . Instead that must be your choice. "Prophylactic" radiation therapy to the brain should also at least be considered. But even with full treatment her prognosis remains very bad unfortunately!

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Oncology (General Cancer)

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Claes-Gustaf Nordquist, M.D.


Questions concerning Cancer, Oncology, radiation Therapy, Tumours, Chemotherapy, Cytotoxic Drugs, Hormonal Therapy, Radiation Protection.


I'm a Doctor of Medicine and specialist in Medical Oncology and Radiation Therapy educated & trained in Sweden. Now retired. Background in Radiation Therapy, Medical Oncology, Radiation Protection, Nuclear Medicine, Diagnostic Radiology, Gynecological Oncology, Clinical Pathology, Clinical Cytology,Hematology and Internal Medicine. M.D. from the faculty of medicine, Royal Karolinska Institute, Stockholm, Sweden. Have also been an exchange student at the Hebrew University, Hadassah Medical School, Jerusalem Israel. Former medical consultant, Swedish National Board of Radiation Protection. Former Police Surgeon and Medical Examiner, Stockholm Police Department. Former Chief Medical Officer, The Royal Guards, The Royal Horse Guards and the Royal Household Brigade, Royal Swedish Army Medical Corps. You can also reach me on: I have no restrictions in the number of questions there. I also answer questions in these other categories: General History, Military History, Brain Tumors, Breast Cancer, Colon Cancer

I'm a medical doctor and specialist in medical oncology and radiation therapy

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