You are here:

Pediatrics/Regarding PENTAXIM and OPV


Hi doctor, my daughter is now 3 and half months old. At Birth, she was given ENGERIX B. Along with that OPV was given. Later on 6 weeks period, PENTAXIM and EngerixB was given. No OPV was given at that time. At 10 weeks, she was given PENTAXIM only. On Jan 31, 2012, we went for her 14th week vaccination. At that time, she was given PENTAXIM, OPV and ROTARIX (1ST DOSE).When i searched through web, it is said that PENTAXIM contains IPV. So is there any problem giving OPV along with PENTAXIM. The first and second time when she was given PENTAXIM, no OPV was given. Also we are planning to go to US. So doctor said that vaccination for Rotavirus and PCV should be taken. One dose of Rotavirus vaccine has been given. When is the next dose to be given. Also doctor said that we can take the PCV vaccine after reaching US. So what is the last time period to take this PCV vaccination ? is it possible to take the third dose of Rotavirus vaccine from US ?

Hi Surya,

There is no problem if OPV is given along with IPV. This was the standard practice to give OPV along with IPV till early this year. However, as per latest Indian recommendations released in July 2012, now IPV is given alone at 6, 10 and 14 weeks followed by OPV at 6 and 9 months of age.

You can see the latest Indian immunization schedule, as recommended by IAP (and accredited by WHO) at:

However, the immunization schedule varies from country to country depending on epidemilogical and other factors. For example, OPV is not used at all in US (as they eradicated polio decades back, unlike in India where we are nearing eradication presently).

In general, one should follow the immunization schedule of the country where the child normally resides. Hence, if you are going to US for short visit and would come back, I would recommend that your baby should be given OPV at 6 and 9 months of age. If you are emigrating to US, then OPV need not be given from now on.

Regarding PCV, 3 doses are recommended at one month interval followed by a booster at 12-15 months. In India, 2 brands are available: Prevenar 13 and Synflorix. However, in US, only Prevenar 13 is available. Since the brands are not interchangeable, I would recommend that you should go for Prevenar 13 only as the schedule can be completed in US safely.

For ROTARIX, only 2 doses are recommeded at one month interval, globally. Third dose is not required/ recommended (3rd dose would have been required if other brand ROTATEQ has been used in place of ROTARIX)

Please feel free to ask for any further clarification.

Best wishes,
Dr. Puneet Kumar,
Kumar Child Clinic, Dwarka,
New Delhi, India.



All Answers

Answers by Expert:

Ask Experts


Dr. Puneet Kumar


I would be happy to answer general queries on prevention and treatment of ailments in newborn, infant, toddler, child or an adolescent. Needless to say, it will not be possible to answer any query that requires diagnosing, since it is not possible to examine a child online.


I have worked in various capacities (medical officer, resident, senior resident, consultant) in public as well as private sector in Pediatrics and Neonatology. Today, I have over 17 years of experience in the field.

Currently, I am running my own clinic (Kumar Child Clinic) in Dwarka, New Delhi and am attached to Lifeline Hospital, Dwarka as consultant pediatrics and neonatology. I am also developing my clinic website into a comprehensive child health/ parenting website (

(a) Chapter "National Immunization Schedule" in Frontiers of Social Pediatrics, Jaypee Publishers: 2nd edition, 2016. (b) Article, "All about Pertussis vaccines" in special issue of Indian Journal of Practical Pediatrics, July-Sept 2015 (c) Three chapters (DTP vaccines, Pneumococcal vaccines and Poliovirus vaccines) in "Textbook of Pediatrics for Post-graduates" First edition: 2015. (c) Chapter: "Alternative delivery methods of vaccines" in IAP textbook of Vaccines, First edition, 2014 (published by IAP/ Jaypee Brothers) (d) Special Article: "50 years of Immunization in India: Progress and Future" in January 2013 issue of Indian Pediatrics (e) Four chapters in "FAQ: Book on Vaccines and Immunization Practices" First edition, 2011 AND 2nd edition, 2015 published by Jaypee Brothers. (f) Three articles in special issue of Journal of Pediatric Sciences on “Controversies and Challenges in Pediatric Vaccination Today" in Sept, 2010. Co-edited the series also. (f) Regular column, “How do I treat” in Pediascene ( (g) Review article, “Role of Anti-Poliovirus Agents in Polio eradication and beyond” in Polio Pulse, April, 2008. (h) Chapter on “Acute Infectious Diarrhea” in Textbook of Infectious Diseases in Children. (An IAP Publication), 2007. 2nd edition in 2011. (i) Book-Review (IAP Pediatric Drug Formulary, 2004) in Pediascene, March 2005 ( ) (j) Case-report on Osteopetrosis. Jharkhand Journal of Pediatrics, Dec-2002.

After MBBS, I have done DNB residency in Pediatrics.

Awards and Honors
Winner of IAP practising pediatrician's quiz in 2001.

©2017 All rights reserved.