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Pediatrics/query regarding vaccines


Hello Doctor.
My daughter is 45 days old.  She was given BCG, OPV 0, Hep B at the time of birth.
Hep B2 on 36th day of her life.  
Now on 44th day of her life she has been given :
Hib 1 + DTaP 1  in a combination ( Brand - Sii HibPRO and Sanofi Pasteur)and IPV 1 of Brand Sanofi Pasteur.

Please let me know
1) whether Hib 1, DTap 1 and IPV  of these brands are actually painless as told by my Doctor and I have been charged Rs.2000/- for the same.

2) Can I give her Pentaxim for the next two dozes of Hib, DTap and IPV in her 10th and 14th week respectively?

3) I am getting her vaccinated for Rotarix within 2 days (46-47th day of her life)

4) I have been suggested 3 dozes + 1 booster of  for Prevenar 13 by my Ped. whereas a relative told me that a single vaccine of 4 dozes has been launched costing Rs. 6000/- instead of Rs. 16,000/- (total cost of 4 dozes)  Is that true?

Hi Tanu,

There are a very serious issues here:

1. If DTaP and Hib vaccine have been given as SEPARATE injections, it is OK. If however, they were mixed in single syringe, it should not have been done, as they are of different manufacturers.
[HoweverDTaP (TRIPACEL) and Hib (Act-HiB) of Sanofi Pasteur can be mixed as per manufacturer's recomendations]

Vaccines of two brands can't be mixed, as no body knows if they are compatible and would be effective.

DTaP and HIb, if given in a single syringe should be ignored and the dose repeated.

Here are other answers:

Yes, DTaP causes much less pain/ fever as compared to DTwP.

Yes, baby can be given Pentaxim (combination of DTaP, Hib and IPV).

Get Rotavirus vaccination as soon as possible (Ideally, vaccination is started at 6 weeks of age).

There is nothing like 4-in-one dose. What your relative might be referring to is Pentaxim (which contains vaccine against 5 diseases: Diptheria, Pertussis, Tetanus, Polio and HiB). And cost of Pentaxim, PCV (Synflorix), and Rotavirus all put together (and adding doctors fee) comes to about Rs. 6000 per dose.

Best wishes,
Dr. Puneet Kumar,
Kumar Child Clinic, Dwarka,
New Delhi, India



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Dr. Puneet Kumar


I would be happy to answer general queries on prevention and treatment of ailments in newborn, infant, toddler, child or an adolescent. Needless to say, it will not be possible to answer any query that requires diagnosing, since it is not possible to examine a child online.


I have worked in various capacities (medical officer, resident, senior resident, consultant) in public as well as private sector in Pediatrics and Neonatology. Today, I have over 17 years of experience in the field.

Currently, I am running my own clinic (Kumar Child Clinic) in Dwarka, New Delhi and am attached to Lifeline Hospital, Dwarka as consultant pediatrics and neonatology. I am also developing my clinic website into a comprehensive child health/ parenting website (

(a) Chapter "National Immunization Schedule" in Frontiers of Social Pediatrics, Jaypee Publishers: 2nd edition, 2016. (b) Article, "All about Pertussis vaccines" in special issue of Indian Journal of Practical Pediatrics, July-Sept 2015 (c) Three chapters (DTP vaccines, Pneumococcal vaccines and Poliovirus vaccines) in "Textbook of Pediatrics for Post-graduates" First edition: 2015. (c) Chapter: "Alternative delivery methods of vaccines" in IAP textbook of Vaccines, First edition, 2014 (published by IAP/ Jaypee Brothers) (d) Special Article: "50 years of Immunization in India: Progress and Future" in January 2013 issue of Indian Pediatrics (e) Four chapters in "FAQ: Book on Vaccines and Immunization Practices" First edition, 2011 AND 2nd edition, 2015 published by Jaypee Brothers. (f) Three articles in special issue of Journal of Pediatric Sciences on “Controversies and Challenges in Pediatric Vaccination Today" in Sept, 2010. Co-edited the series also. (f) Regular column, “How do I treat” in Pediascene ( (g) Review article, “Role of Anti-Poliovirus Agents in Polio eradication and beyond” in Polio Pulse, April, 2008. (h) Chapter on “Acute Infectious Diarrhea” in Textbook of Infectious Diseases in Children. (An IAP Publication), 2007. 2nd edition in 2011. (i) Book-Review (IAP Pediatric Drug Formulary, 2004) in Pediascene, March 2005 ( ) (j) Case-report on Osteopetrosis. Jharkhand Journal of Pediatrics, Dec-2002.

After MBBS, I have done DNB residency in Pediatrics.

Awards and Honors
Winner of IAP practising pediatrician's quiz in 2001.

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