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Question
Thank you so much for answering my question Debbie. I have 250 mg of clavamox and 10-20mg of predisone . Do you know where I could get smaller amounts? I am so worried that she is suffering and not there to see her condition.
Thanks for any help.
Tsake Care Debbie

Answer
You don't need smaller amounts. Didn't I send you instructions on how to mix up the amoxicillin?  If not, i'll add it below.

For the prednisone:  For a 10 mg tablet, mix with 2 ml of flavoring, and then the dose is 0.2 ml/lb twice a day.

For a 20 mg tablet, mix with 4 ml of flavoring, and then the dose is 0.2 ml/lb twice a day.
Deb

To mix amoxicillin:

You need to know about how much your rat weighs.  The dose is 10 mg/lb twice a day but you can safely go as high as 50 mg/lb.  In most cases (check the package) each amoxicillin capsule contains 250 mg, which is 25  1-lb doses.  

If you have access to small syringes for measuring (a 1 ml syringe or insulin syringes with the top broken off) you can mix the amoxicillin in a liquid.  Amoxicillin does not dissolve but forms a suspension.  The powder will sink to the bottom, so before taking out a dose, you need to stir the mixture with the syringe extremely well, being sure to scrape up all the powder off the bottom so it is in suspension.

Mix one capsule of 250 mg amoxicillin in 7.5 ml of flavoring such as Ensure or slightly diluted Hersheyís strawberry syrup. (If you have 500 mg capsules, use twice the amount of flavoring: 15 ml.) A small pill bottle is about the right size to mix it in.  Keep in the refrigerator.  Amoxicillin doesnít taste too bad to most rats and most rats will eagerly lick this right from the tip of the syringe.  The normal dose is 0.3 ml/lb twice a day.  (Note: 1 cc = 1 ml = 100 units on an insulin syringe, so 0.3 ml = 30 units.)  You can go as high as 5 times that normal dose if necessary, and itís a good idea to give a double dose the first time.

If your rat wonít take the amoxicillin mixture voluntarily, you can make the dose 0.1 ml which is too small for them to spit out when you put it in the back of their mouth.  Mix one capsule with 2.5 ml of flavoring. Then the dose is only 0.1 ml/lb twice a day.

If you donít have small syringes, you can mix it in food.  Dump a capsule out on a plate.  If it is granular, grind it to a powder.  Divide the powder in half, and half again, etc.  Until you have 24 piles. Since itís hard to divide it more than this, you can give the 1-lb dose to rats who weigh less than a pound.   Itís better to give too much than not enough.  Scrape a pile into a little bit of food such as baby food, mashed avocado, etc.  

Give the dose twice a day.  If it's going to work the symptoms should improve within 2-3 days.  If it does work you need to continue the treatment for at least 2-3 weeks.  If it doesnít work then you need to try a different treatment.  If the symptoms are all gone within 3 days you should continue the treatment for 3 weeks.  If it takes longer for all the symptoms to go away, give it for 4-8 weeks and maybe longer.  The longer it takes for all the symptoms to go away, the longer you should continue the treatment.  If the symptoms stop improving, or if the amoxicillin doesn't help at all, you will need to try doxycycline instead.

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Debbie Ducommun

Expertise

I can answer any questions about pet rats, but you will probably be able find answers to simple questions more quickly on my website at www.ratfanclub.org/helpfinfo.html. If you have a life-threatening emergency you can try calling me at 530-899-0605. I am not usually on the computer on the weekend.

Experience

I have been "The Rat Lady" since 1985 and am recognized as one of the world's experts on pet rats. I have 3 published books and already answer lots of questions about rats daily.

Organizations
President of Rat Assistance & Teaching Society

Publications
I am a monthly columnist for Pet Business magazine, and my writing has appeared in other magazines. I have 3 published books.

Education/Credentials
BA in Animal Behavior

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