About Joshua Cappuccilli Expertise I can answer most questions involving medication use, side effects, adverse effects, interactions and how drugs relate to specific disease states. Noone can answer all questions; I will respond as such if I cannot provide an answer. I will provide resources / references for the information that I use to formulate the answer given.
Experience I am a PharmD with my degree from the University of FLorida - currently I am preparing to take the state boards in Florida.
Organizations California Phamacist Association
American Pharmacy Assocaition
Education/Credentials BA University of South Florida
PharmD University of Florida
Question Hi Joshua,
I think this is sort of a pharmacology question...if you are unable to answer, any references to further research will be appreciated.
I'm interested in the idea that topical caffeine possibly helps to break down fat in cellulite and I'm trying to make some caffeine preparation of my own rather than buy a product.
1)So, in what form will the caffeine be more available: strong brewed coffee or crushed, dissolved caffeine tablets?
2)Obviously, in order to apply the caffeine to my skin and leave it there to sink in, I need to mix it with a base. So what do you think would work best: aqueous cream/glycerine/soap/etc ? (I assume some substances might 'hold' the caffeine on the surface of the skin while others may release it more effectively...??).
3)And finally, any ideas on how to increase skin permeability? (...if it isn't unhealthy to regularly do so..).
I realise I've squeezed more than a few questions in here. Any of your expert suggestions will be very welcome, thank-you.
-C
Answer This will not work. There are a number of reasons but the main one is that for caffeine to work as an assistant medication for weight loss it needs to act centrally - stimulating the body to potentially consume more calories - it will not act locally to decrease fat / adipose tissue deposits. Also, caffeine is not a reliable or safe compound to use for weight loss because of short half-life, the stress it places on the body, the need for increased doses and closer dosing times and the potential for withdrawal effects when it needs to be stopped.
