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Pharmacology/sulfa drugs
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Question
A couple years ago I used a dye on my hair that contained PPDA (para-phenylenediamine)and developed somewhat of an allergic reaction after awhile in the form of itching and inflammation. I was told to be careful using 'sulfa' drugs after that. I googled 'sulfa drugs' and found that they contain "sulfonamides" and that "it is important to make a distinction between sulfa drugs and other sulfur-containing drugs and additives, such as sulfates and sulfites, which are chemically unrelated to the sulfonamide group, and do not cause the same hypersensitivity reactions seen in the sulfonamides. My question is, is the topical gel or lotion commonly used for acne, Sodium Sulfacetamide with Sulfur, in the sulfonamide group and considered a sulfa drug, or is it one of those that isn't? Thanks
Lee-
Yes, sulfacetamide is a sulfonamide and can cause the same allergic reactions.
Sulfonamides are an organic combinations of sulfur and substituted ammonia which are distinct from sulfur atoms by themselves.
Sulfonamides are found in many drug products like diuretics (furosemide, hydrochlorothiazide) and sunscreens that contain para-aminobenzoic acid.
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Answers by Expert:
Joe Haynes, R.Ph., MBA
Expertise
I can answer pharmacy/pharmacology questions as they relate to both pediatric and adult therapies. Please note that since I practice in Florida that I may not be able to answer specific questions regarding pharmacy practice in your state. As a disclaimer, I have no financial interest in recommending or failing to recommend any drug product. My goal is to give you the best answer to your questions regardless of product.
Experience
I have 24 years experience in pharmacy practice including pediatric and adult hospital, home-infusion, and long-term care (nursing home/ALF). I enjoy assisting with pediatric dosing and medication questions since children respond differently and are dosed differently than adults. I can help you determine if the dose you want to administer to your child is appropriate. I am currently director of pharmacy for a small community hospital in St. Petersburg, FL.
Organizations
Florida Society of Health-Systems Pharmacists
American Society of Health-Systems Pharmacists
Florida Pharmacy Association
Education/Credentials
BS in Microbiology from Auburn University (1989)
BS in Pharmacy from Northeastern University (1994)
MBA (generalist) from St. Leo University (2005)
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