Expert: Dr Mohd Tariq Salman - 6/6/2009

Question
QUESTION: dear expert
first of all thank you so much for your effort to make people informed about Aids and make mind about their cases.
i have a question for u please,
last week i took a tetanus immune globulin (tig ) shot after an accident on my hand.
i dont know why i had a bad thoughts about that shot if it transmit blood borne pathogens as hiv hbv hvc
the shot named tet human 250 iu made in france bellon
is that way to transmitt hiv or hcv
thank u indeed sir

ANSWER: Dear Ammar, Assalam u alaikum.All immune globulins, including tig are sterile and do no possess the risk of transmission of any infection, including hiv or hcv.

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QUESTION: thanks a lot for ur answer
i had my fears after i read this page
Risk of Transmissible Agents in Plasma-derived Preparations

http://www.medscapecrm.net/druginfo/monograph?cid=med&drugid=150460&drugname=Tet(PF)+IM&monotype=monograph&secid=4

and did tetanus ig (tig) enough to get immunization and for how long
thanks again dr.tarik





ANSWER: The link you have given is not working. Please copy the article, paste on MS Word and send me at mtariqsalman[at the rate]gmail.com. Tetanus immune globulin (TIG) is used to provide passive immunity to tetanus as part of a postexposure prophylaxis regimen following a tetanus-prone wound and also in the treatment of tetanus in conjunction with active immunization with tetanus toxoid adsorbed or anti-infective agents against Clostridium tetani respectively. It only provides short term protection due to passive immunization and is not a substitute for active immunization with tetanus toxoid adsorbed. For effective immunization you need tetanus toxoid adsorbed.

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QUESTION: thanks a lot doctor
this is another link
http://www.druglib.com/druginfo/baytet/warnings_precautions/
i will send u a pdf on yr email
do u advise me to get tetanus booster now or later
and what is the short time the tig immunization do?
again u r such a kind doctor
thank u very much for yr answers
ammar

Answer
Thanks for the pdf. During manufacture, donors are screened for any diseases, then various processes are used for inactivation of viruses and sterilization. So, practically there is no risk. But no process is fool proof. That's why the warning is written. Half life of the Immune globulin is 23 days which means its concentration in blood becomes half in 23 days. If you had taken the shot of tig because of any wound, it is enough for you. For protection from future infections,if you like, you can start tetanus toxoid immunization right now, but its not mandatory. It will be sufficient to take immunization as per the recommendations within 24 hours after having a wound.