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About Joshua Cappuccilli
(Top Expert on this page)

Expertise
I can answer most questions involving medication use, side effects, adverse effects, interactions and how drugs relate to specific disease states. Noone can answer all questions; I will respond as such if I cannot provide an answer. I will provide resources / references for the information that I use to formulate the answer given.

Experience
I am a PharmD with my degree from the University of FLorida - currently I am preparing to take the state boards in Florida.

Organizations
California Phamacist Association American Pharmacy Assocaition

Education/Credentials
BA University of South Florida PharmD University of Florida

   

You are here:  Experts > Health/Fitness > Pharmacology > Pharmacology

Questions Answered By Expert  Joshua Cappuccilli 
In Category  Pharmacology

SubjectDate Asked

Statins and alcohol7/22/2008
  Q: I have high cholesterol levels (~280 total, LDL was 187, others were about where they should be). ...
  A: You are probably going to be fine at normal levels of consumption - please understand that NORMAL is ...
Plavix7/15/2008
  Q: I have been told that I have to take Plavix, and cannot afford it. I see that Canadadrugs.com has a ...
  A: There was a generic available in the US that is currently tied up in litigation and not available ...
What is a drug?7/12/2008
  Q: Mr.Cappuccilli, my question derives from hearing about athletes being penalized for taking ...
  A: I believe that if I took a dose of sugar before a race, my performance would be enhanced, but sugar ...
medicine7/12/2008
  Q: my wife had back surgery about 4 yrs ago,since she has taken several pain medications,the last ...
  A: It really depends on the test that she was tested with / or used. It is not possible for the ...
epi pens?7/10/2008
  Q: How long does an epi (epinephrine pen) last and how long does a glucagon pen last? Also what is the ...
  A: q) How long does an epi (epinephrine pen) last and how long does a glucagon pen last? a) I am not ...
increase skin permeability?5/29/2008
  Q: I think this is sort of a pharmacology question...if you are unable to answer, any references to ...
  A: This will not work. There are a number of reasons but the main one is that for caffeine to work as ...
Hair loss and Chantix?5/28/2008
  Q: My girlfriend has taken Chantix for 2.5 months. She's never missed a pill and it achieved success ...
  A: CHantix is a relatively new medication but it does not have a documented causality for hair loss ...
Converting from Lortab to Methadone for pain5/27/2008
  Q: My first question would be is what would be the conversion from Lortab 7.5 mg. two q.i.d. to ...
  A: My first question would be is what would be the conversion from Lortab 7.5 mg. two q.i.d. to ...
synthroid for weight loss?4/25/2008
  Q: A little over a month-ago, I was put on a diet plan by my doctor which includes Adipex 37.5, Lasix ...
  A: Unless you are hypo thyroid (meaning you have low thyroid function) there is not a long term benefit ...
vyvance4/24/2008
  Q: My husband started vyvance five days ago. He liked how the drug made him feel. However, today he ...
  A: Karin, Vyvance is a (relatively) short lived medication - meaning it will be out of his system ...
hgh releaser4/16/2008
  Q: i have an extremely athletic 14 yoa daughter and an 11 yoa son. they take vitamins on a regular ...
  A: That would not be beneficial and may be harmful for your children. First, HGH is at it's highest ...
opioid antagonists4/7/2008
  Q: if someone decided to repeatedly use opioid antagonists (e.g. naloxone), would the withdrawal ...
  A: No - they would not be euphoric - it probably would not be fun either. It certainly would not be ...
Veterinary drug use4/7/2008
  Q: I'm not sure if im asking this question in the right forum but here goes anyway. A friend of mine ...
  A: You should not take this drug - it does not burn fat. It is not made for humans - it is ...
Antihistamines4/5/2008
  Q: I'm taking Claritin for seasonal allergies. If I find that it's not quite doing the job on some ...
  A: These are (obviously) both antihistamines. Claritin produces less sedation than benadryl ...
Klor-con4/5/2008
  Q: My daughter, age 19) just stopped taking Yasmine which was prescribed for her acne. She had been ...
  A: The klor-con is a commonly used medicine. I have to say that I admire you for reading the label BUT ...
St John's Wort and ASA4/4/2008
  Q: I am taking 81mg of coated aspirin daily as an anticoagulant,which my cardiologist has prescribed ...
  A: The website you looked at is right - St. John's wort potentiates (or may) the effect of ...
How would one know?3/31/2008
  Q: How would one know if a pharmacy mistakenly filled a prescription with the wrong drug? I know it is ...
  A: Well - the good news is that it is a cipro 500 tablet. The tablet is produced by Abrika ...
How would one know?3/31/2008
  Q: How would one know if a pharmacy mistakenly filled a prescription with the wrong drug? I know it is ...
  A: It is not as unlikely as one would really hope it was. Follow-up with another question to me - ...
Drug-drug interactions3/27/2008
  Q: Can there be any drug-drug interactions (increased/decreased plasma levels) between paroxetine CR ...
  A: Robert - there is an interaction between SSRI's and TCA medications. The following is taken from ...
drug testing3/24/2008
  Q: if taking vyvance and a drug test is done is it possible to test positive for methamphetamine or ...
  A: Guaranteed to test positive. Vyvance IS an amphetamine. If you have taken it within 48 to 72 hours ...
breathing difficulties relating to medication3/23/2008
  Q: Any medication i take appears to depress my respiratory system and gives me very bad breathing ...
  A: You must have heard this before but it may be psychosomatic. It is unlikely that all medications ...
Nasonex3/16/2008
  Q: My husband has been on nasonex for approximately one year. During the past two months he has been ...
  A: Yes. After a prolonged therapy stopping medications can cause a "rebound" effect (meaning that it ...
prilosec3/15/2008
  Q: Does taking prilosec over a period of time (months at least) pose any dangers?
  A: Unless you are in a group of patients that is at risk already extended therapy is safe. There is a ...
how long does valium stay in your system3/15/2008
  Q: My husband was abusing valiums (benzodiazepams) for a period of about 2 weeks he bought them in ...
  A: It will take 30-45 days if there is no further use. It is a lipid (fat) distributed drug and takes a ...
sleep help3/8/2008
  Q: 30 AM. In order to help me sleep early and not toss & turn, I have been taking a dose of Nyquil. ...
  A: 30 AM. In order to help me sleep early and not toss & turn, I have been taking a dose of Nyquil. ...
hot rubs3/6/2008
  Q: First, I'd like to thank you again for the extremely helpful answer you gave to a question I asked ...
  A: Yes - there is no 'healing' involved. The counter irritants may work secondarily like you are ...
hot rubs3/5/2008
  Q: First, I'd like to thank you again for the extremely helpful answer you gave to a question I asked ...
  A: Rubs like Ben-Gay and others that primarily use menthol (or similar ingredients) are "counter ...
What is the legal way of disposing of drugs?2/27/2008
  Q: I am involved in an environmental group that is concerned about sewage sludge. Should we be ...
  A: This is a VERY complicated question. The reason it is so complicated is that the regulations vary ...
Adderall2/21/2008
  Q: Yesterday I took 4adderall they were 20mg,and two white pills with the letter M on it.Now last time ...
  A: Alyssa - from the price and limited description it is possible that you got ativan but that would be ...
Adderall2/21/2008
  Q: Yesterday I took 4adderall they were 20mg,and two white pills with the letter M on it.Now last time ...
  A: Alyssa - what are you doing? I am going to skip the whole "you should not be doing this" thing that ...
XANAX & UA DETECTABILITY2/21/2008
  Q: HOW LONG WOULD ONE ISOLATED 1MG DOSE OF XANAX/ALPRAZOLAM TAKE TO BE UNDETECTABLE IN A URINE ...
  A: Depending on your body composition up to 4 weeks - the more body fat you have the longer it will ...
Augmentin 1000 XR2/21/2008
  Q: My dr. prescribed this drug 2 pills am and 2 piss pm. I couldn't swallow them and he told me to ...
  A: There is nothing that can be done to remove the augmentin from your system. From what you have said ...
caffeine elimination2/20/2008
  Q: Does any method, technique, or drug exist which is able to accelerate the elimination of caffeine ...
  A: Caffeine elimination is enzymatically driven and cannot be accelerated without other drugs that MAY ...
Metformin & Vitamin Supplement2/18/2008
  Q: I am taking metformin 850mg BID. I've read that metformin interferes with B vitamin absorbtion. ...
  A: You are correct that it is listed as a potential side effect of the medication. The research and ...
Adderall2/7/2008
  Q: Okay,on Tuesday around 9am I took 5 adderall i don't know what mg's they were. The at about 10:30 I ...
  A: You should feel loads better every day if you keep up drinking juices, gatorade, water and ...
Adderall2/7/2008
  Q: Okay,on Tuesday around 9am I took 5 adderall i don't know what mg's they were. The at about 10:30 I ...
  A: You need to do what I said earlier - peeing a lot without drinking is not helping - as your urine ...
Adderall2/7/2008
  Q: Okay,on Tuesday around 9am I took 5 adderall i don't know what mg's they were. The at about 10:30 I ...
  A: The Adderall XR is designed to release the drug over a 12 hour period. Based on the timeline that ...
Pain meds2/2/2008
  Q: Joshua, I have a question about pain Medicine? I have epilepsy, which I take Carbatrol 700mg a ...
  A: There are more than one option that may be helpful in your circumstance. First, the MOTRIN that you ...
Maximum dosages1/14/2008
  Q: I am planning to speak to my doctor about increasing the dose of a medication I am taking. In the ...
  A: It is interesting that you took that the way you did - but what I meant was that your doctor may (or ...
Maximum dosages1/14/2008
  Q: I am planning to speak to my doctor about increasing the dose of a medication I am taking. In the ...
  A: Joan, The dosing schedules and maximum daily doses can be found in the prescription information ...
Prostatitis1/7/2008
  Q: I was being treated for and am currently being treated for prostatitis. About 1.5 years ago i was ...
  A: This is not supported by the current literature but that does not mean that it is wrong (4 days of ...
Reaction or Not?1/7/2008
  Q: In the past I have had some itching after taking antibiotics so I have stopped them, I was recently ...
  A: If you are not having a significant reaction you may ask your doctor or pharmacist if you can ...
Advil Migraine1/3/2008
  Q: I know that Advil sells a product targeted toward migraine sufferers (like myself). When I read the ...
  A: This is a marketing gimmik. There is a slight SLIGHT difference in the time that it takes the ...
muscle aches1/3/2008
  Q: I have found your answers to my previous questions edifying, on subjects of real concern to me, and ...
  A: 1) except now I'm wondering, in the face of your saying that it is as a result of the systemic ...
naproxen/stomach issue1/3/2008
  Q: I have been having, in recent weeks, a stomach problem that puzzles me, but that I'm wondering if it ...
  A: I've been giving some thought to your counsel, in particular to the part about "topical analgesic ...
Effexor XR for hot flashes1/3/2008
  Q: Greetings, I experienced chemo-induced menopause 5 years ago and was put on Effexor XR for hot ...
  A: ALL OF THESE DRUGS (THE WINE INCLUDED) ARE CONSIDERED TO BE POTENTIAL OR ACTUAL CNS DEPRESSANTS - SO ...
Expired Paroxetine1/2/2008
  Q: I ran out of paroxetine and will not be able to get to my doctor for a few more days - I have left ...
  A: There is no real way to answer this - by regulatory mandate the expiration date is usually one year ...
naproxen/stomach issue12/31/2007
  Q: I have been having, in recent weeks, a stomach problem that puzzles me, but that I'm wondering if it ...
  A: A couple of follow-ups. 1) I have avoided acetominophen for some years, because I've observed ...
naproxen/stomach issue12/31/2007
  Q: I have been having, in recent weeks, a stomach problem that puzzles me, but that I'm wondering if it ...
  A: For a long time, I was taking it without having this problem: is it possible that over time, my ...
Side effects of Nitrofurantonin12/21/2007
  Q: I've been taking 50mg of Nitrofurantonin at night for about 2 months to prevent urine infections. I ...
  A: This is a relatively RARE but potentially IRREVERSIBLE OR SEVERE side effect of NITROFURANTOIN. ...
Anti-Itch Lotion12/21/2007
  Q: My mom uses "SARNA Anti-Itch Lotion." It works well for her. Is there an equivalent to SARNA that ...
  A: THe active ingredients in SARNA are fairly common - camphor and menthol are in any number of ...
Manerix (Aurorix)12/19/2007
  Q: I am aware that 300mg of manerix provides MAO-A (serotonin) inhibition at 80%. Does this give us an ...
  A: In animal testing Paroxetine is shown to be one of the most potent drugs in this class (more potent ...
Manerix (Aurorix)12/19/2007
  Q: I am aware that 300mg of manerix provides MAO-A (serotonin) inhibition at 80%. Does this give us an ...
  A: I AM USING ALL CAPS TO DIFFERENTIATE FROM YOURI am aware that 300mg of manerix provides MAO-A ...
Elimination is saturated means?12/11/2007
  Q: What does it means when its say elimination is saturated at high doses?
  A: Elimination is saturated at high doses is exactly what it says - it means that the mechanism by ...
HF/Pletal12/8/2007
  Q: My nearly 90 year old father with severe HF, severe CKD, and severe PAD, has just been prescribed ...
  A: BASED ON A REVIEW OF THE AVAILABLE LITERATURE I CANNOT DISAGREE WITH THE RECOMMENDED MEDICATION. ...
toxicity of lithium & other meds12/7/2007
  Q: I am a 33 y/o female in overall good health except for the following: bipolar 2 disorder and ...
  A: First, consider yourself VERY VERY fortunate - it can be exceedingly challenging to get a BPD ...
TRAMADOL 50 MG11/30/2007
  Q: IS TRAMADOL CONSIDERED A NARCOTIC? I WORK IN A NURSING HOME IN TEXAS AND IT IS NOT IN THE LOCKUP ...
  A: IS TRAMADOL CONSIDERED A NARCOTIC? I WORK IN A NURSING HOME IN TEXAS AND IT IS NOT IN THE LOCKUP ...
Birth Control and Acid11/28/2007
  Q: I will be using my Loestrin 24 FE soon when my next P comes, which should be in a few days. But my ...
  A: There are no interactions that I am aware of for this drug combination. I would note that you ...
HRT11/28/2007
  Q: I have two que,1.if someone is suffering from low levels of testerone is advisible to take dhea,and ...
  A: 1.if someone is suffering from low levels of testerone is advisible to take dhea,and what is the ...
Vyvance side effects11/26/2007
  Q: Recent history first if it is needed....Been taking Wellbutrin XL for about 2 weeks. He switched me ...
  A: I can say that I am glad to hear that you are stopping the Vyvance for the time being. The ...
Vyvance side effects11/24/2007
  Q: Recent history first if it is needed....Been taking Wellbutrin XL for about 2 weeks. He switched me ...
  A: Carol I appreciate how frustrating it can be trying to get a treatment that works for you. First ...
Seroquel and Gabapentin11/20/2007
  Q: According to you, is it normal that a small dose, 25mg of Seroquel would give muscle twitches? I'm ...
  A: According to you, is it normal that a small dose, 25mg of Seroquel would give muscle twitches? ...
dietary or natural alternative to vicodin's calming effect11/15/2007
  Q: I was prescribed some vicodin to manage pain after an accident. I took one pill a day for about 3 ...
  A: Vicodin has the same class active ingredient as Opium - the root drug family - opiates are powerful ...
Vitamin A11/13/2007
  Q: I'm getting into a very physical sport called Parkour. I've started taking L-Glutamine, Ribose, Cod ...
  A: Your confusion is just related to the units. Your medication (multivitamin) has 4200IU - 4200 ...
SSRIs11/7/2007
  Q: some SSRIs does not cause insomnia. why?
  A: Zahra - sorry about the delay in answering your question. In short, all SSRI's can cause insomnia ...
alcohol and drugs11/2/2007
  Q: I take fluoxetine 40mg each morning and vytorin 10/40 each evening. I drink 5-6 beers Fri, Sat, and ...
  A: First, I've often tried to make some sort of general assessment of my alcohol intake on the basis of ...
alcohol and drugs11/1/2007
  Q: I take fluoxetine 40mg each morning and vytorin 10/40 each evening. I drink 5-6 beers Fri, Sat, and ...
  A: Kevin - as with many things there are not generally "hard answers". When I first started studying ...
novo venlafaxine xr 37.5 mg10/30/2007
  Q: "I have been prescribed this medication for anxiety. I had recently had a c-1 NUCCA (National ...
  A: That is a great question. First, let me say that anti depressants are not only used for depression. ...
Neurontin or Pregabalin10/29/2007
  Q: Do you think it's a good alternative to be taking Neurontin or Pregabalin in the purpose of stopping ...
  A: Jennifer - your question is a very good one. I have done some checking and have (unfortunately) ...
SEEK IMMEDIATE MEDICAL ATTENTION10/28/2007
  Q: do you advice me to use sitalopram for me? i am really sad and commited suicide more than 3 times .i ...
  A: YOU NEED TO SEEK IMMEDIATE MEDICAL ATTENTION. YOU CAN GET THE HELP YOU NEED BY CALLING 911 AND ...
Evening primose oil10/28/2007
  Q: I normally take evening primose oil (EPO) on a regular basis. Will taking that cause an increse in ...
  A: I checked the national database that deals with EPO (it can be found at: ...
Side effects10/27/2007
  Q: how are you going? Thank you for taking the time to answer my question. I recently took the ...
  A: There is really no way to assess your problem from the information given - diagnosis is only done by ...
Vd calculation10/26/2007
  Q: why it is easier to use an intravenous bolus dose of a drug to calculate the Vd rather than using an ...
  A: We use IV bolus for Vd calculation because there is (virtually) no lag time between administration ...
side effects10/24/2007
  Q: i have been taking daytime and night time tabs along with ceftin 250 2time a day and i have been ...
  A: I don't know what the active ingredients in the Walmart Day / Night cold formulations are however, ...
side effects10/24/2007
  Q: i have been taking daytime and night time tabs along with ceftin 250 2time a day and i have been ...
  A: Tiffany, I need a little more information to better answer your question. 1) What kind of daytime & ...
SEMI-LOG PLOT10/24/2007
  Q: Drug metabolism can be affected by genetic polymorphisms. Sulphadimidine is known to show ...
  A: With a SEMI-LOG plot the results for a slow metaboliser would be a flatter slope. If the Y value is ...
drugs10/24/2007
  Q: What steps are involved in sulphadimidine metabolism?
  A: Sulfadimidine is well absorbed orally, and distributed widely to various tissues and fluids. T½ = ...
Vd of sulphadimidine10/24/2007
  Q: Would the Vd of sulphadimidine differ between an individual who was a fast metaboliser and someone ...
  A: Yes. BE ADVISED THAT THIS IS THE BEST ANSWER I CAN PROVIDE - Pharmakokinetics and Pharmacology are ...
DMSO & NaHCO3 TOPICAL SOL'N10/23/2007
  Q: CAN I COMBINE DIMETHYL SULFOXIDE AND BAKING SODA TO MAKE A SIMPLE TOPICAL SOLUTION OR SHOULD I GET ...
  A: You should be very carefull with this SOLVENT. Without knowing what you intent is for this topical ...

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