AboutDr Alan Galbraith Expertise I can answer most questions on drugs, both medical and "recreational". Answers can be given in either technical or layperson terminology. My main areas of interest are psychiatric, gastrointestinal and cardiovascular drugs.
Experience I have been a university lecturer/head of department for almost thirty years, but am now retired. My research interests were alcohol, smoking and cardiovascular disease.
Organizations Institute of Biology, London.
Publications Author of "Fundamentals of Pharmacology" 5th Edition published in November 2007 by Pearson Education, Australia.
Question Do these drugs interact to cause tachycardia? Someone suggested that they do, but the TCA can do this alone.Is there some protein pump action with the TCA's which can enhance this?
Answer
Sorry Robert but protein pumps do not enter the equation.
Dear Robert
Both can cause tachycardia although the Anafranil is the most likely to. Whether there is an additive effect I do not know but it is possible. The most likely drug is certainly the Anafranil. Depending upon an ECG will determine whether a change in drug is required unless the tachy is very fast and cause physical stress I would not stop any drug until you see your prescriber.