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About Nigel Simmons
Expertise
I am happy to answer general questions on medicines and hospital care. If possible, please use approved / chemical names rather than brands which are not internationally recognised. Like all health professionals I am bound by a duty of care which prevents me giving detailed information about medication or treatment of people other than the questioner. I will endeavour to help wherever possible or point towards more appropriate advice. If however your question crosses too far into patient confidentiality, I hope you will understand why I cannot answer your question. Consider.. would you want me to discuss your care with a friend or relative without your knowledge?

Experience
Registered as a UK pharmacist in 1982 and have worked in a number of hospital and health management posts around the UK. Formerly Chief Pharmacist for a 440 bed general hospital in Cambridgeshire.
Past/Present clients
Previously Sysop on CompuServe UK Professionals forum.

 
   

You are here:  Experts > Health/Fitness > Pharmacology > Pharmacy > citalopram vs escitalopram

Topic: Pharmacy



Expert: Nigel Simmons
Date: 2/21/2008
Subject: citalopram vs escitalopram

Question
I have been taking antidepressants for awhile now and recently moved to a new state - thus needing a new doctor.  I needed a new script for Lexapro (escitalopram). When I went to fill it I was told there was no generic.  I thought that is what my other doctor prescribed and was given the generic (citalopram - this is what it said on my old bottle).  Are these interchangable or does my new doctor need to write me a script specifically for citalopram?
Thanks for your help.

Answer
Raina

In clinical terms there is no real difference between citalopram and eiscitalopram. The latter was introduced by the manufacturers as a means of protecting their profits as the original citalopram came to the market with a short patent life (so short period of exclusive business).

Citalopram is effectively a mix of the same drug but with "left" and "right" hand structures. In developing eiscitalopram, the makers effectively seived out one type which is less active and then sold the more active isomer as eiscitalopram.

As eiscitalopram is only the more active component, its dose is smaller than citalopram. Therefore, in switching back to citalopram the dose should be approximately doubled. If this is done, I would not expect any problems with switching.

Generic citalopram will be significantly cheaper than branded eiscitalopram.

I hope this helps.

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