AboutDr. Ravindra Bhaskar Ghooi Expertise I can provide information on drugs and medicines, their actions, uses, interactions and adverse effects. To avoid confusion, generic names of
medicines may please be provided. I am a pharmacologist, having worked
on animal and human pharmacology, and presently I am the Dean of Bilcare Research Academy, where we teach courses on clinical research. We dont work on saturdays and sundays, hence questions reachng me on these days will be replied on Monday, please bear with me.
Question I am 65 years old, a type 2 diabetic for 10 years, but kept it always under control at 6.4 (Canada standards) by taking Metformin ½ pill two times per day.
Because I started to have high blood pressure 150/98 in the morning, this January the doctor gave me Coversyl 8mg/day . The blood pressure went down nicely to 130/85 in the morning and even lower during the day, but my problem now is that the blood sugar level increased to 8.3 without changing anything in my diet. I cannot understand what is happening because Coversyl is supposed to lower the blood sugar.
Answer Hi Kurt,
We do know that the response of the body to some drugs reduces over time, and this is true for metformin. The highest dose of metformin is around 2 tablets (of 500 mg) three times a day, so you are at a very early stage of this reduction in response. My guess is that your dose has to be increased. However dosages of antidiabetic should be adjusted with care and under directions of a local physician. I see no problem in this, you need to talk to your doctor and he may either step up the dose or add a drug like glibenclamide to your present dose.
Ravi Ghooi
