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You are here: Experts > Health/Fitness > Pharmacology > Pharmacy > phobia depression
Pharmacy - phobia depression
Expert: Dr Alan Galbraith - 10/22/2009
Question QUESTION: dear sir,
how is DULOXETINE 30 MG for depression and anxity, is it effect to liver? and what are its sexual side effect.
ANSWER: Dear Majid
The sexual adverse effects and percentage affected are as follows: erectile dysfunction (impotence), (5%); ejaculation disorder (4%); abnormal orgasm, delayed ejaculation (3%); anorgasmia (no orgasm) (at least 1%).
It does not appear to affect the liver but should only be used with caution in persons with abnormal liver function.
Regards
Alan Galbraith
---------- FOLLOW-UP ----------
QUESTION: dear sir,
can i take nortripytilne 10 mg at bet time along with fluvoxamine 50 mg , there will be any interaction if i take fluvoxamine 50 mg in the morning and nortripytiline 10 mg at bed time or i can have it , is it safe?
Answer Dear Majid
Fluvoxamine can increase the toxicity of nortriptyline therefore the combination must only be used under careful supervision. Check with your prescriber as to this. Personally I would not recommend this combination.
Regards
Alan galbraith
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