Respected Sir, I am writing after a long time. I am 58 years male obese diabetic and hypertensive. I am on Atenolol 100 once HCTZ 25 mg Losartan 50 mg twice and Amlodepine 50 mg twice.
Due to elevation in BP, 180/90 my internist added Minipress XL 5 mg. Due to its side effectsI was scared and started with prazocin 2.5 in the night. After 10 days hangover is there but bp is in range of 140/85. When I vonsulted my internist he asked me to replace with Arkamin 100 twice daily.
My point is should I continue Minipress XL 5 mg or 2.5 to optimise its efficacy. I think there are no options for me. I am also afraid of Arkamin. I may inform that I have urine frequency in night also.
I started with prazocin 2.5 due to apprehension of side effects.
Kindly suggest me. Regards
Yours is an interesting question. What would suit a person with your profile, prazosin as a plain tablet or as an extended release tablet (Minipress XL)?
My opinion is, when in doubt, avoid XL preparations. The reason I say this, is that XL preparations have long effect, while with normal formulations the effect is for short time. If you find problems with prozosin (plain), you can discontinue it immediately. So the choice of prazosin is in my opinion a good choice.
About urination at night. I recently felt the same problem and hence did a thorough literature search. Yes the frequency of urination increases with age and there is nothing we can do about it.
So please continue with prazosin in the morning, try out another dose at night, if it makes you uncomfortable discontinue the evening dose, continue the drug only in the morning.
This should solve your problem.
All the best