Expert: Dr Alan Galbraith - 1/19/2004

Question
Can you tell me the adverse effects and nursing interventions for Abilify (aripiprazole) and Lexapro (citolopram)?  Thanks!

Answer
Dear Mira

Here is the info on citalopram.

The increased use of SSRIs in the management of
depression is widely thought to underlie a rise in the
observed rates of a relatively uncommon, toxic, and
potentially fatal, condition called serotonin syndrome.
This syndrome is associated with a hyperserotonergic
state characterised by euphoria, drowsiness, abnormal
muscle movements, sweating, intoxication, hyperthermia,
diarrhoea, loss of consciousness and, possibly, death.
receptor to its transmitter will

To avoid the serotonin syndrome in the use of SSRIs,
it is beneficial to prevent the co-administration of
antidepressant agents, have an adequate washout period
when switching drugs, and avoid administering a high
dose of a single drug. Even if the dose is progressively
increased, SSRIs do not generally lead to better control
of depression. All SSRIs are also relatively safe in an
overdose; however, toxicity is increased if they are taken
with other agents.

Adverse Reactions: GI upset; somnolence; dry mouth; sweating; tremor; ejaculation disorder; bleeding abnormalities