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About Eric Brandt
Expertise
I am a practicing pharmacist.On my drug information website, I have answered hundreds of questions to date. The articles posted on my site include Parkinson`s disease. depression, menopause, diabetes, sleep and aging, congestive heart failure, calcium channel blockers, thyroid hormone replacement therapy, ADHD, multiple sclerosis an more.

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I have experience in retail as well as hospital pharmacy pracice. Currently working in a hospital pharmacy. I am experienced in drug information. Over the last 6 years I have developed a successful web site for drug information.

The addressfor my drug information website is http://www.druginformation.bc.caThere you can read articles on varios areas of health interest. You can also leave me questions which I will personally answer. I also have a free health information newsletter called The Caplet. To subscribe send e-mail to thecaplet-subscribe@topica.com
 
   

You are here:  Experts > Health/Fitness > Pharmacology > Pharmacy > aggrenox or plavix

Pharmacy - aggrenox or plavix


Expert: Eric Brandt - 1/26/2007

Question
I am a 66yo male ischemic stroke victim, which happened in Nov. 05. I have since been treated with Plavix once a day, and I have, on my own, also added aspirin, 325 mg once a day, which may be a bit risky.
 I have since been told by 2 other neurologists that they would have started me on Aggrenox instead of Plavix.  The best I can find out by internet research is that Plavix acts by coating platelets with a smooth surface so they won’t stick together, and the active ingredient in Aggrenox, ER-DP, acts as a vasodilator. Is there any information  or study addressing the theory that a combination of these would add symbiotically ?


Answer
Hi Frank,
Aggrenox contains dipyridamole and ASA. Dipyridamole's mechanism of action is much like that of Plavix in that they both affect adenosine mediated plaelet aggregation. It would not make sense to combine drugs with similar mechanisms of action.
Thank you for using Allexperts
Sincerely,
Eric Brandt, B.Sc. Pharm

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