Expert: Dr. Tara Kompare, Pharm.D. - 5/4/2007

Question
Hello,
My nephew is 5 months old. He was born with Spina Bifida of the L4L5 area.  He is having bladder control issues and the urologist is worried about the pressure in his bladder being to high. One treatment option is to take Ditropan (anticholinergic) for life to decrease this pressure.  I'm wondering what the long term side effects of taking this type of medication would be and if there is a safer medication alternative? Another consideration is that he does have trouble with intermittent constipation as is common for Spina Bifida kids.
Thank you for your help!

Answer
Dear Chenoa,

As far as I know, there are no other alternatives that are superior to Ditropan. And, unfortunately, one of the side effects of Ditropan, and any anticholinergic drug, is constipation. If you are concerned, I would seek a second opinion from a doctor who specializes in treating babies with spina bifida. It never hurts to get a second opinion.

When starting medications like Ditropan in babies, the doctor only prescribes such drugs when the benefit clearly outweighs the risk. With proper dosing and monitoring, hopefully Ditropan will help your nephew rather than hurt.

I wish your nephew and your family the best. Take care and good luck!

Regards,
Dr. Tara Kompare, Pharm.D.