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You are here: Experts > Health/Fitness > Pharmacology > Pharmacy > depression and seroquil
Expert: Mary E Scott, RPh, CGP
Date: 12/29/2007
Subject: depression and seroquil
Question
"i have been put on seroquel for anxiety plus mirtazapine can you let me know the side effects of coming off these medications as i believe i was wrongly diagnosed as delusional and psychotic. Doctors tried to fool me into thinking i was put on them for anxiety i am on 60mg of mirtazapine a day and 25mg of seroquel. I have been on these meds for around 9 weeks, my anxiety has not improved but gotten worse and now i actually do feel depressed i was on ativan and had a seizure after coming off it under a drs guidance. does this make me more likely to have problems coming off stated drugs? Is seroquil really used for anxiety and if not psychotic can it cause me to become so by going off it? How can a dr get things so wrong all i was suffering was extreme anxiety i am 55 yrs of age and have never had a mental illness unless you count anxiety as such. Are the two drugs safe to take together? I have found this has ruined my life and some days cannot think straight mainly due to the worry of being put on them. Can i safely cut the mirtazapine down to 30mgs? Thank you for any help you may offer Angie"
Answer
Hi,Angeline,
Normally, mirtazepine is used for depression and/or insomnia. It is not usually used for anxiety and 60mg is a pretty high dose. 15-45mg daily is recommended for depression
Seroquel (quetiapine) is an antipsychotic med used for schizophrenia, bipolar disorders. It is not used for anxiety.
I think you need to get a second opinion from a psychiatrist especially if you are not getting relief from the anxiety you are experiencing.
I would not cut down the mirtazepine to 30mg, but you could try to decrease to 45mg until you can get an appointment with another doctor. I would not recommend going off either med without a doctor's OK.
Hope this helps, Mary
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