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About Nigel Simmons
Expertise
I am happy to answer general questions on medicines and hospital care. If possible, please use approved / chemical names rather than brands which are not internationally recognised. Like all health professionals I am bound by a duty of care which prevents me giving detailed information about medication or treatment of people other than the questioner. I will endeavour to help wherever possible or point towards more appropriate advice. If however your question crosses too far into patient confidentiality, I hope you will understand why I cannot answer your question. Consider.. would you want me to discuss your care with a friend or relative without your knowledge?

Experience
Registered as a UK pharmacist in 1982 and have worked in a number of hospital and health management posts around the UK. Formerly Chief Pharmacist for a 440 bed general hospital in Cambridgeshire.
Past/Present clients
Previously Sysop on CompuServe UK Professionals forum.

 
   

You are here:  Experts > Health/Fitness > Pharmacology > Pharmacy > novo venlafaxine xr

Pharmacy - novo venlafaxine xr


Expert: Nigel Simmons - 5/15/2007

Question
QUESTION: Hi, I have been taking novo venlafaxine xr: 37.5 mg a day (for anxiety) for the last 3 days and I am wondering what happens if I suddenly decide to stop taking the pills? I am also curious to know if it is normal to be feeling somewhat lightheaded in the beginning. Thank you.
ANSWER: Julie

It sounds as though you are experiencing common side effects of Venlafaxine (see www.drugs.com/mtm/venlafaxine.html). These will often settle as you become more established with the medication. As you are taking the sustained release formulation, these problems should be lower, but not necessarily nil.

If however you find these symptoms intolerable, it should be quite safe to stop the drug at this stage. However, once established it is often necessary to slowly withdraw the medication to prevent other symptoms. Regrettably most of the newer anti-depressant and anti-anxiety medication are associated with withdrawal problems.

My suggestion would be to consider whether the side effects are making you more anxious and if so it may be better to discontinue. Many anxety states respond to motivational change and you may consider that the potential for side effects is not comfortable and that you may find that with a positive outlook your anxiety could  be reduced. If you can achieve this, the recognition that you feel better and more positive is the starting point for the next step along the road.

I hope this helps.

---------- FOLLOW-UP ----------

QUESTION: Dr.,
How long until the meds become "established" as you say? If I choose to 'wait and see' for a few more days, I don't want to run the risk of allowing them to establish and then have to deal with withdrawal. On the other hand, I don't want to stop without giving this a fair shot, especially if it will help me in the end. Thank you again.

Answer
Julie

As you are taking a sustained release (long acting) formulation, it will usually take 7-10 days before a static blood level is reached. Full therapeutic effect will typically be within two to three weeks. Hopefully as the drug becomes more effective your side effects will decrease because you feel better in yourself and your body adjusts to the medication.

If however the side effects worsen, then it would be advisible to stop and discuss an alternative product. Although Venlafaxine is one of a class of drugs which have a common mechanism of action, side effects can vary between patients and between products. You may find that you tolerate an alternative product better.


If you find your symptoms of anxiety improving, then that is a positive move forward.  

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