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Rabbits/Marbocyl dosage too high?


Hi Dana,

My rabbit was just prescribed Marbocyl for a possible mouth infection. She just had her teeth filed down, but she's still drooling. They gave me 80mg tablets that are usually used for dogs and told me to give 3/4 of a tablet per day for 5 days. I gave her the dose yesterday, and she seems okay. The drooling has all but stopped.  But it seemed like a really high dose, and I have to give 4 more, so I looked online and could only find that the recommended dosage is 2-5mg/kg. She weighs 4.5 kilos, so if I gave 5mg per kilo that would only come out to 22.5 mg. And the dose they told me to give is 60 mg.

I live in the Czech Republic (Eastern europe) and this vet is supposed to be the rabbit expert in town. It took me a long time to find a vet that files teeth down with proper tools rather than clips them. So, I have no option here for a second opinion. The dose for metacam that they gave me was pretty high, too - 1 ml per 24 hours of 1.5 ml suspension. I've only been doing .5 ml and it works just fine.

Can you verify if my concerns are correct? Should I cut the dose back to a half tablet or less? From what I read, a too high dose of Marbocyl can lead to seizures. Thank you so much for any info you can give me.

Dear Julie,

The dose we generally use for marbofloxacin is 20mg/kg once per 24 hours.  Metacam can be dosed up to 1mg/kg every 24hours.

Because you don't say how much your rabbit weighs, I can't tell what dose she is getting.  But I hope this helps.

Drooling is usually a sign of molar spurs or other dental disorder:

I hope this helps.



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Dana Krempels, Ph.D.


I've lived with companion rabbits for more than 35 years, and consider them members of my family. I can answer any questions about the biology and health of rabbits, from the commonplace to the unusual. But please note:

RULE #1:

Find a rabbit vet at for immediate help, and don't risk your bunny's life by spending time asking questions online! If you can't get in touch with your vet, read these Emergency Sick Bunny Instructions.

If you have found a wild baby rabbit, please read these EMERGENCY INSTRUCTIONS FOR WILD BABY RABBITS and then use this link to FIND A LOCAL WILDLIFE REHABILITATOR who can give you the right advice.

RULE #2:
Help me help you! Please make your subject line informative if you have an urgent question. then LET ME KNOW IN THE SUBJECT LINE so I can give your question highest priority over non-urgent questions. If you don't do this, then I can't guarantee timely assistance!

For all the best, most accurate rabbit health, care and behavior information, visit The House Rabbit Society.


I have been rescuing and rehabilitating domestic and wild rabbits for about 30 years. I have written articles for many rabbit rescue publications, as well as for the veterinary journal, Exotic DVM. I own EtherBun, the internet's largest listserve dedicated to health, care, and behavior of domestic rabbits.

Houserabbit Adoption, Rescue, and Education, Inc. (H.A.R.E., Inc.) president National House Rabbit Society (Board member)

Exotic DVM
Warren Peace (Journal of the House Rabbit Society of Miami)
Various newsletters of the House Rabbit Society, nationwide

Ph.D - Biology
B.S. - Biology
B.A. - English

Awards and Honors
Lightspan Academic Excellence Award for web site on rabbit health and biology

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