Thyroid Problems/High Ferritin - Liver - Low Testosterone
QUESTION: Hello Dr,
I have just had my blood test results come in.
I weight lift, eat well, use supplements and am in good condition. I am in my early 40's.
My ferritin is going up and up and up on each blood test, my cholesterol has gone down from 8.8 to 6.7. My ferritin has risen a lot on the past three blood tests (242 - 287 - 367).
Here are my recent blood test results;
TSH - 0.5 mIU/L ( Reference range - 0.3 - 3.5 )
Free T4 - 14.9 pmol/L ( Reference range - 9.0 - 19.0 )
Prolactin - 110 mIU/L ( Reference range - less than 500 )
Total PSA - 0.29 ug/L ( Reference range - 0.25 - 2.2 ) Lab comments say I am below the norm for a male in my early 40's and prostate neoplasia may be a concern?? What the??
Cortisol - 267 nmol ( Reference range - 100 - 535 )
Sodium - 141 mmol/L ( Reference range - 135 - 145 )
Potassium - 4.7 mmol/L ( Reference range - 3.5 - 5.5 )
Chloride - 107 mmol/L ( Reference range - 135 - 145 )
Bicarbonate - 21 mmol/L ( Reference range - 20 - 32 )
Anion Gap - 13 mmol/L ( Reference range - 5 - 15 )
Ca (corr) - 2.34 mmol/L ( Reference range - 2.10 - 2.55 )
Phosphate - 1.1 mmol/L ( Reference range - 0.8 - 1.5 )
Urea - 5.6 mmol/L ( Reference range - 3.0 - 8.0 )
Urate - 0.40 mmol/L ( Reference range - 0.20 - 0.50 )
Creatinine - 73 umol/L ( Reference range - 60 - 110 )
eGFR - >90 ( Reference Range - >59 )
Fast Glucose - 5.6 mmol/L ( Reference range - 3.6 - 6.0 )
Random Glucose - 4.7 mmol/L ( Reference range - 3.6 – 7.7 )
Total Protein - 74 g/L ( Reference Range - 66 - 83 )
Albumin - 47 gL ( Reference Range - 39 - 50 )
Globulin - 27 g/L ( Reference Range - 20 - 39 )
T Bilirubin - 12 umol/L ( Reference range - 4 - 20 )
ALP - 60 U/L ( Reference Range - 35 - 110 )
AST - 40 U/L ( Reference Range - 10 - 40 )
ALT - 66 U/L ( Reference Range - 5 - 40 )
GGT - 33 U/L ( Reference Range - 5 - 40 )
LDH - 193 U/L ( Reference Range - 120 - 250 )
Cholesterol - 6.7 mmol/L ( Reference range - 3.9 - 5.5 )
Haemolysis Index - 11 ( Reference Range - 0 - 40 )
Testosterone - 8.5 nmol/L ( Reference Range - 11.0 - 40.0 )
Iron - 25 umol/L ( Reference Range - 5 - 30 )
Transferrin – 2.3 g/L ( Reference Range – 1.9- 3.1 )
TIBC - 57 umol/L ( Reference Range - 45 - 72 )
Saturation - 44% ( Reference Range - 20 - 55 )
Ferritin - 367 ug/L ( Reference Range - 30 - 300 )
What do you think?
Thanks so much!
Low PSA is always indicative of low testosterone levels. I dont consider you are at risk of prostate cancer. But you can go for abdominal/pelvic ultrasound. Any medicines you take daily? for hypertension or some other condition? What supplements you take may I know? Since you do weight lifting I would recommend echocardiography for screening cardiomyopathy. Cardiomyopathies can sometimes present as high ferritin levels. Do you consume alcohol? Usage of marihuana/cannabis? What is your profession? height and weight? Any recent weight loss? History of hypertension or Diabetes?
---------- FOLLOW-UP ----------
QUESTION: Thanks for your reply.
I am in my early 40's. I have never smoked, never done any kind of drugs and I do not drink. I do not take any steroids either.
I eat healthy and avoid the bad stuff foods.
I weight about 250lbs and am 5'-11", most of this is muscle and am approximately 15% body fat. I have not had any sudden loss in weight. In fact, I probably would say that I find it difficult to get really lean or gain muscle.
Supplements, I take the following;
R Lipoic Acid
Accetyl L Carnitine
I have an office job where I sit behind a PC most of the day.
I do not have any diabetes and I think my mother has this, but it is probably due to weight issues.
If I am not wrong, some of supplements you are taking are used for natural treatment of hair loss or alopecia. So they might be suppressing your testosterone levels. So my recommendation is You consult an andrologist and show him what supplements you are taking. Discuss with him what effects they might have on testosterone DHT etc. Since your TSH is borderline low get thyroid antibodies checked. Serum FSH, gonadotropin, estrogen levels need to be checked. Next step would be performing Ultrasound/testes. ALT is normally high in people who do weight training. Not an issue. Your iron profile doesnt seem to be alrming either.